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Anti-MICB Antibody (3I896)
还可以产品编号 TMAY-01131
别名 PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (3I896) 是一种 Mouse 抗体，靶向 MICB。Anti-MICB Antibody (3I896) 可用于 ELISA,FCM。
Anti-MICB Antibody (3I896)
Anti-MICB Antibody (3I896)
还可以产品编号 TMAY-01131 别名 PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody (3I896) 是一种 Mouse 抗体，靶向 MICB。Anti-MICB Antibody (3I896) 可用于 ELISA,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 595 | 5日内发货 | |
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MICB Antibody (3I896) is a Mouse antibody targeting MICB. Anti-MICB Antibody (3I896) can be used in ELISA,FCM. |
| 别名 | PERB11.2, MHC class I polypeptide-related sequence B |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3I896 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of anti-MICB on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with purified mouse anti-MICB. Second step staining with rabbit anti-mouse IgG FC polyclonal antibody. |
| 应用 | ELISA,FCM |
| 推荐剂量 | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human MICB protein (TMPY-01066) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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