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顶部生物活性储存和溶解信息计算器

Anti-MICB Antibody (3I896)

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产品编号 TMAY-01131

别名 PERB11.2, MHC class I polypeptide-related sequence B

Anti-MICB Antibody (3I896) 是一种 Mouse 抗体，靶向 MICB。Anti-MICB Antibody (3I896) 可用于 ELISA,FCM。

Anti-MICB Antibody (3I896)

Anti-MICB Antibody (3I896)

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产品编号 TMAY-01131 别名 PERB11.2, MHC class I polypeptide-related sequence B

Anti-MICB Antibody (3I896) 是一种 Mouse 抗体，靶向 MICB。Anti-MICB Antibody (3I896) 可用于 ELISA,FCM。

规格价格库存数量
20 μL
¥ 595
5日内发货
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-MICB Antibody (3I896) is a Mouse antibody targeting MICB. Anti-MICB Antibody (3I896) can be used in ELISA,FCM.
别名PERB11.2, MHC class I polypeptide-related sequence B
Ig Type
Mouse IgG1
克隆号
3I896
交叉反应
Human
特异性
Human MICB
验证活性
Flow cytometric analysis of anti-MICB on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with purified mouse anti-MICB. Second step staining with rabbit anti-mouse IgG FC polyclonal antibody.
应用ELISAFCM
推荐剂量
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human MICB protein (TMPY-01066)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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