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Anti-MICB Antibody-FITC (3I896)
还可以产品编号 TMAY-01131F
别名 PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody-FITC (3I896) 是一种 FITC-conjugated Mouse 抗体，靶向 MICB。Anti-MICB Antibody-FITC (3I896) 可用于 FCM。
Anti-MICB Antibody-FITC (3I896)
Anti-MICB Antibody-FITC (3I896)
还可以产品编号 TMAY-01131F 别名 PERB11.2, MHC class I polypeptide-related sequence B
Anti-MICB Antibody-FITC (3I896) 是一种 FITC-conjugated Mouse 抗体，靶向 MICB。Anti-MICB Antibody-FITC (3I896) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 T | ¥ 680 | 5日内发货 | |
| 100 T | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MICB Antibody-FITC (3I896) is a FITC-conjugated Mouse antibody targeting MICB. Anti-MICB Antibody-FITC (3I896) can be used in FCM. |
| 别名 | PERB11.2, MHC class I polypeptide-related sequence B |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3I896 |
| 交叉反应 | Human |
| 验证活性 | Analysis of anti-MICB on HeLa cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MICB / MIC-B (rh MICB; TMPY-01066; NP_005922.2; Met 1-Gly 298) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related protein, both of which contain three extracellular immunoglobulin-like domains, but without the capacity to bind peptide or interact with beta-2-microglobulin. acting as a stress-induced self-antigen, binding of MICB to the NKG2D receptor activates the cytolytic response of natural killer (NK) cells, CD8+αβ T cells, and γδ T cells on which the receptor is expressed. MICA/B is minimally expressed on normal cells, but are frequently expressed on epithelial tumors and can be induced by bacterial and viral infections. MICA/B recognition thus is involved in tumor surveillance, viral infections, and autoimmune diseases. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human MICB protein (TMPY-01066) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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