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Anti-AASS Polyclonal Antibody

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货号 TMAB-02131

Anti-AASS Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AASS。Anti-AASS Polyclonal Antibody 可用于 WB。

Anti-AASS Polyclonal Antibody

Anti-AASS Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02131

Anti-AASS Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AASS。Anti-AASS Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-AASS Polyclonal Antibody is a Rabbit antibody targeting AASS. Anti-AASS Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrial
组织特异性Expressed in all 16 tissues examined with highest expression in the liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Alpha-aminoadipic semialdehyde synthase (AASS), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), is a 926 amino acid protein that exists as a homodimer in the mitochondria. AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation. It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation. Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), autosomal recessive disorders characterized by hyperlysinemia, lysinuria, and variable saccharopinuria. However, no adverse mental or physical effects have been found in patients with hyperlysinemia.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LKRSDH
抗原种属
Human
基因名称
AASS
基因ID
蛋白名称
alpha-aminoadipic semialdehyde synthase, mitochondrial
Uniprot ID
功能
Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
化学信息
分子量Theoretical: 99 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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