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顶部生物活性储存和溶解信息计算器

Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 2

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Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 2
产品编号 TMAC-04305
别名 YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)

Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-YAP1 (Ser127)。Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 可用于 WB,IHC,IF。

Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 2

Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 2
产品编号 TMAC-04305 别名 YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)

Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-YAP1 (Ser127)。Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody 可用于 WB,IHC,IF。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody is a Rabbit antibody targeting Phospho-YAP1 (Ser127). Anti-Phospho-YAP1 (Ser127) Polyclonal Antibody can be used in WB,IHC,IF.
别名YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from COS7 tissue using YAP (Phospho-Ser127) antibody TMAC-04305. The lane on the right is treated with the antigen-specific peptide.
2. Immunofluorescence analysis of Hela cell. 1,YAP (phospho Ser127) Polyclonal Antibody (red) was diluted at 1:200 (4°C overnight).
3. Immunohistochemistry analysis of paraffin-embedded human heart , using YAP (Phospho-Ser127) Antibody. The picture on the right is blocked with the phospho peptide.
应用
WB
IHC
IF
推荐剂量
WB: 1:500-1000; IF: 1:50-200; IHC: 1:100-300
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine127(A-H-S(p)-S-P) derived from Human YAP
抗原种属
human
Uniprot ID
P46937
化学信息
分子量Actual: 65 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Yes-associated protein YAP65 homologYes-associated protein 1YAP65YAP1 (pSer127)YAP1 (pS127)YAP1 (phospho-Ser127)YAP1 (phospho-S127)YAP1YAP 65YAP 1Transcriptional coactivator YAP1pYAP1 (Ser127)pYAP1 (S127)Protein yorkie homolog

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