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Anti-MYC Antibody (5D921) 是一种 Mouse 抗体,靶向 MYC。Anti-MYC Antibody (5D921) 可用于 WB。
Anti-MYC Antibody (5D921) 是一种 Mouse 抗体,靶向 MYC。Anti-MYC Antibody (5D921) 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,340 | 5日内发货 | |
100 μL | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-MYC Antibody (5D921) is a Mouse antibody targeting MYC. Anti-MYC Antibody (5D921) can be used in WB. |
别名 | bHLHe39 |
Ig Type | IgG1 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from 293 cells transfected with recombinant human Myc using Myc mouse mAb TMAC-02700. |
应用 | |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Antibodies were produced from mice ascites by injecting mice with a monoclonal cell line which was fusioned by mouse spleen and SP2/0 myeloma cell. Spleen cells were isolated from mice by immunizing with synthetic peptide and KLH conjugates. |
性状 | Liquid |
缓冲液 | Supplied in mice ascites. |
研究背景 | Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates |
偶联 | Unconjugated |
免疫原 | Peptide sequence derived from C-terminal (aa. 410-432) of human c-Myc conjugated with KLH |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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