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Anti-MYC Antibody (5D921)

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Anti-MYC Antibody (5D921)
产品编号 TMAC-02700
别名 bHLHe39

Anti-MYC Antibody (5D921) 是一种 Mouse 抗体,靶向 MYC。Anti-MYC Antibody (5D921) 可用于 WB。

Anti-MYC Antibody (5D921)

Anti-MYC Antibody (5D921)

Rating icon 还可以
Anti-MYC Antibody (5D921)
产品编号 TMAC-02700 别名 bHLHe39

Anti-MYC Antibody (5D921) 是一种 Mouse 抗体,靶向 MYC。Anti-MYC Antibody (5D921) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,340
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100 μL
¥ 2,185
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产品介绍

生物活性
产品描述
Anti-MYC Antibody (5D921) is a Mouse antibody targeting MYC. Anti-MYC Antibody (5D921) can be used in WB.
别名bHLHe39
Ig Type
IgG1
交叉反应
Human
验证活性
1. Western blot analysis of extracts from 293 cells transfected with recombinant human Myc using Myc mouse mAb TMAC-02700.
应用
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Antibodies were produced from mice ascites by injecting mice with a monoclonal cell line which was fusioned by mouse spleen and SP2/0 myeloma cell. Spleen cells were isolated from mice by immunizing with synthetic peptide and KLH conjugates.
性状Liquid
缓冲液Supplied in mice ascites.
研究背景Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide sequence derived from C-terminal (aa. 410-432) of human c-Myc conjugated with KLH
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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