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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PRSS8 Polyclonal Antibody

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货号 TMAB-11839

Anti-PRSS8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRSS8。Anti-PRSS8 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-PRSS8 Polyclonal Antibody

Anti-PRSS8 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-11839

Anti-PRSS8 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRSS8。Anti-PRSS8 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PRSS8 Polyclonal Antibody is a Rabbit antibody targeting PRSS8. Anti-PRSS8 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Prostasin: Cell membrane; Single-pass membrane protein. Prostasin light chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus. Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
组织特异性Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PRSS8 is a member of the trypsin family of serine proteases. It can be found in seminal fluid and is highly expressed in prostate epithelia. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. The carboxyterminal region contains a GPI anchor sequence, which anchors prostasin to the cell surface. Phospholipase activity is thought to liberate prostasin from the cell, and cleavage of the linker region also releases prostasin. PRSS8 has been proposed as a marker for ovarian cancer, where it is up-regulated, a marker for androgen-refractory prostate cancer, where it is down-regulated, and as an inhibitor of invasiveness in breast cancer.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PRSS8
抗原种属
Human
基因名称
PRSS8
基因ID
5652
蛋白名称
Prostasin
Uniprot ID
Q16651
功能
Possesses a trypsin-like cleavage specificity.
化学信息
分子量Theoretical: 30/33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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