frα

FR-167356 是 a3 异构体液泡型 H+-ATPase 的特异性抑制剂，对破骨细胞质膜、肾刷状缘膜和巨噬细胞微粒体的 IC50 分别为 170 nM、370 nM 和 220 nM。 FR-167356 减少 B16-F10 细胞的骨转移。

FR 180204 是一种 ATP 竞争性的选择性ERK 抑制剂，对ERK1和ERK2的Ki 值分别为 0.31 μM 和 0.14 μM，IC50值分别为0.51 μM 和0.33 μM。

Mirvetuximab soravtansine (IMGN853) 是一种靶向叶酸受体α （FRα） 的抗体-药物偶联物（ADC），抑制细胞生长，增强 DNA 损伤的抗增殖效果，可用于研究耐药卵巢癌。

FR252384 is an antagonist of the neuropeptide Y-Y5 receptor (IC50: 2.3 nM).

FR194738 是一种角鲨烯环氧酶抑制剂，在 HepG2 细胞匀浆中的 IC50 为 9.8 nM。

FR194738 free base 抑制 HepG2 细胞匀浆中的角鲨烯环氧酶活性，IC50 为 9.8 nM。

FR 167653 (FR 167653 sulfate) is effective in treating inflammation, relieving trauma and ischemia-reperfusion injury in vivo. FR 167653 , an orally active and selective p38 MAPK inhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity.

FR 900261, Antibiotic WF 3161 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124069，CAS号为 86402-37-1。

FR 58664 is a drug to treat heart failure disease.

FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).

FR-190809 is a nonadrenotoxic and orally efficacious inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) (IC50: 45 nM).

FR167344 free base is an orally active, nonpeptide antagonist of the bradykinin receptor B2, exhibiting high-affinity binding (IC50: 65 nM) and showing no binding affinity for the B1 receptor.

FR-145715 作为一种组胺H2受体拮抗剂，展现出针对幽门螺杆菌的特异性抗菌活性，常用于研究胃部病变。

FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) 是一种口服有活性的、选择性的 COX-1 抑制剂（IC50:28 nM）。它在体内具有镇痛、抗炎、抗血小板的功能。

Protease-activated receptor 1 antagonist

FR 900137 is a new antibiotic agent from a new strain of Streptomyces.

FR-008I is an antibiotic.

FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.

FR 110302 is a potent inhibitor of 5-lipoxygenase.

FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.

FR 62765 is a derivative of WF-3681, an aldose reductase inhibitor.

FR64822(N-(4-pyridylcarbamoyl)amino 1,2,3,6,-tetrahydropyridine), a novel non-opioid antinociceptive compound, displays antinociceptive activities in a variety of assays with mice and rats. It has a strong antinociceptive activity in the acetic acid writh

FR 75513 inhibits the contraction of guinea pig detrusor muscle .

FR 76830 is a synthesised bradycardiac agent.