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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-NGFR Monoclonal Antibody (9G794)

Synonyms: TNFRSF16, p75NTR, p75(NTR), NGFR, Gp80-LNGFR, CD271
货号 TMAT-0750 一键复制产品信息
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Anti-NGFR Monoclonal Antibody (9G794) 是一种 Mouse 抗体，靶向 NGFR。Anti-NGFR Monoclonal Antibody (9G794) 可用于 IF,FCM。

Anti-NGFR Monoclonal Antibody (9G794)

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Rating icon 还可以
货号 TMAT-0750

别名 TNFRSF16, p75NTR, p75(NTR), NGFR, Gp80-LNGFR, CD271

Anti-NGFR Monoclonal Antibody (9G794) 是一种 Mouse 抗体，靶向 NGFR。Anti-NGFR Monoclonal Antibody (9G794) 可用于 IF,FCM。

Anti-NGFR Monoclonal Antibody (9G794)
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产品介绍

生物活性
产品描述
Anti-NGFR Monoclonal Antibody (9G794) is a Mouse antibody targeting NGFR. Anti-NGFR Monoclonal Antibody (9G794) can be used in IF,FCM.
别名
TNFRSF16, p75NTR, p75(NTR), NGFR, Gp80-LNGFR, CD271
Ig Type
IgG1
克隆号
9G794
反应种属
Human
应用IFFCM
推荐剂量
IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGFR p75 plays a central role in the regulation of cell number by apoptosis in the developing CNS. During early development, activation of NGFR p75 by NGF induces apoptotic cell death in some neuronal cells, probably through activation of the sphingomyelinase/ceramide pathway, the ICE like proteases and the JNK pathway. In rat Schwann cells, NGF binding to NGFR p75 activates NF kappaB, possibly to modulate Schwann cell migration during nerve regeneration. CD271 has recently been described as being expressed in mesenchymal stem cells (bone marrow stromal cells).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human NGFR expressed in E. Coli.
抗原种属
Human
基因名称
NGFR
基因ID
4804
蛋白名称
Tumor necrosis factor receptor superfamily member 16
Uniprot ID
P08138
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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