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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-FAS Monoclonal Antibody (6M108)

Synonyms: TNFRSF6, FASTM, FAS1, CD95, APT1, APO-1, ALPS1A
货号 TMAT-0940 一键复制产品信息
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Anti-FAS Monoclonal Antibody (6M108) 是一种 Mouse 抗体，靶向 FAS。Anti-FAS Monoclonal Antibody (6M108) 可用于 WB,IF,FCM。

Anti-FAS Monoclonal Antibody (6M108)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0940

别名 TNFRSF6, FASTM, FAS1, CD95, APT1, APO-1, ALPS1A

Anti-FAS Monoclonal Antibody (6M108) 是一种 Mouse 抗体，靶向 FAS。Anti-FAS Monoclonal Antibody (6M108) 可用于 WB,IF,FCM。

Anti-FAS Monoclonal Antibody (6M108)
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产品介绍

生物活性
产品描述
Anti-FAS Monoclonal Antibody (6M108) is a Mouse antibody targeting FAS. Anti-FAS Monoclonal Antibody (6M108) can be used in WB,IF,FCM.
别名
TNFRSF6, FASTM, FAS1, CD95, APT1, APO-1, ALPS1A
Ig Type
IgG1
克隆号
6M108
反应种属
Human
应用WBIFFCM
推荐剂量
WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human FAS expressed in E. Coli.
抗原种属
Human
基因名称
FAS
基因ID
355
蛋白名称
Tumor necrosis factor receptor superfamily member 6
Uniprot ID
P25445
化学信息
分子量Theoretical: 37.7 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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