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Anti-PYK2 Monoclonal Antibody (6M943) 是一种 Mouse 抗体,靶向 PYK2。Anti-PYK2 Monoclonal Antibody (6M943) 可用于 WB,IHC。
别名 PTK2B, PTK, PKB, FRNK, FAK2, CAKB
Anti-PYK2 Monoclonal Antibody (6M943) 是一种 Mouse 抗体,靶向 PYK2。Anti-PYK2 Monoclonal Antibody (6M943) 可用于 WB,IHC。

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| 产品描述 | Anti-PYK2 Monoclonal Antibody (6M943) is a Mouse antibody targeting PYK2. Anti-PYK2 Monoclonal Antibody (6M943) can be used in WB,IHC. |
| 别名 | PTK2B, PTK, PKB, FRNK, FAK2, CAKB |
| Ig Type | IgG2a |
| 克隆号 | 6M943 |
| 反应种属 | Human |
| 应用 | WBIHC |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | PTK2B |
| 基因ID | |
| 蛋白名称 | Protein-tyrosine kinase 2-beta |
| Uniprot ID |
| 分子量 | Theoretical: 115.8 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |