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Anti-IGF1R Monoclonal Antibody (4C146) 是一种 Mouse 抗体,靶向 IGF1R。Anti-IGF1R Monoclonal Antibody (4C146) 可用于 WB,FCM。
别名 JTK13, IGFR, IGFIR, CD221
Anti-IGF1R Monoclonal Antibody (4C146) 是一种 Mouse 抗体,靶向 IGF1R。Anti-IGF1R Monoclonal Antibody (4C146) 可用于 WB,FCM。

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| 产品描述 | Anti-IGF1R Monoclonal Antibody (4C146) is a Mouse antibody targeting IGF1R. Anti-IGF1R Monoclonal Antibody (4C146) can be used in WB,FCM. |
| 别名 | JTK13, IGFR, IGFIR, CD221 |
| Ig Type | IgG2a |
| 克隆号 | 4C146 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | IGF1R |
| 基因ID | |
| 蛋白名称 | Insulin-like growth factor 1 receptor |
| Uniprot ID |
| 分子量 | Theoretical: 154.8 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |