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Anti-MET Monoclonal Antibody (6D311)

Synonyms: RCCP2, HGFR, DFNB97, c-Met, AUTS9
货号 TMAT-0762 一键复制产品信息
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Anti-MET Monoclonal Antibody (6D311) 是一种 Mouse 抗体,靶向 MET。Anti-MET Monoclonal Antibody (6D311) 可用于 WB,IHC,IF,FCM。

Anti-MET Monoclonal Antibody (6D311)

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货号 TMAT-0762

别名 RCCP2, HGFR, DFNB97, c-Met, AUTS9

Anti-MET Monoclonal Antibody (6D311) 是一种 Mouse 抗体,靶向 MET。Anti-MET Monoclonal Antibody (6D311) 可用于 WB,IHC,IF,FCM。

Anti-MET Monoclonal Antibody (6D311)
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产品介绍


生物活性
产品描述
Anti-MET Monoclonal Antibody (6D311) is a Mouse antibody targeting MET. Anti-MET Monoclonal Antibody (6D311) can be used in WB,IHC,IF,FCM.
别名
RCCP2, HGFR, DFNB97, c-Met, AUTS9
Ig Type
IgG1
克隆号
6D311
反应种属
Human,Monkey
应用WBIHCIFFCM
推荐剂量
WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human MET (AA: 743-932) expressed in E. Coli.
抗原种属
Human
基因名称
MET
基因ID
蛋白名称
Hepatocyte growth factor receptor
Uniprot ID
化学信息
分子量Theoretical: 155 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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