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Anti-FGFR4 Monoclonal Antibody (9Z569) 是一种 Mouse 抗体,靶向 FGFR4。Anti-FGFR4 Monoclonal Antibody (9Z569) 可用于 IF。
别名 TKF, JTK2, CD334
Anti-FGFR4 Monoclonal Antibody (9Z569) 是一种 Mouse 抗体,靶向 FGFR4。Anti-FGFR4 Monoclonal Antibody (9Z569) 可用于 IF。

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| 产品描述 | Anti-FGFR4 Monoclonal Antibody (9Z569) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (9Z569) can be used in IF. |
| 别名 | TKF, JTK2, CD334 |
| Ig Type | IgG1 |
| 克隆号 | 9Z569 |
| 反应种属 | Human |
| 应用 | IF |
| 推荐剂量 | IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line. |
| 抗原种属 | Human |
| 基因名称 | FGFR4 |
| 基因ID | |
| 蛋白名称 | Fibroblast growth factor receptor 4 |
| Uniprot ID |
| 分子量 | Theoretical: 87.9 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |