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Anti-FGFR4 Monoclonal Antibody (9Z569)

Synonyms: TKF, JTK2, CD334
货号 TMAT-0919 一键复制产品信息
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Anti-FGFR4 Monoclonal Antibody (9Z569) 是一种 Mouse 抗体,靶向 FGFR4。Anti-FGFR4 Monoclonal Antibody (9Z569) 可用于 IF。

Anti-FGFR4 Monoclonal Antibody (9Z569)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0919

别名 TKF, JTK2, CD334

Anti-FGFR4 Monoclonal Antibody (9Z569) 是一种 Mouse 抗体,靶向 FGFR4。Anti-FGFR4 Monoclonal Antibody (9Z569) 可用于 IF。

Anti-FGFR4 Monoclonal Antibody (9Z569)
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产品介绍


生物活性
产品描述
Anti-FGFR4 Monoclonal Antibody (9Z569) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (9Z569) can be used in IF.
别名
TKF, JTK2, CD334
Ig Type
IgG1
克隆号
9Z569
反应种属
Human
应用IF
推荐剂量
IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide.
浓度1 mg/mL
研究背景FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
抗原种属
Human
基因名称
FGFR4
基因ID
蛋白名称
Fibroblast growth factor receptor 4
Uniprot ID
化学信息
分子量Theoretical: 87.9 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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