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Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)

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产品编号 TMAY-01475P
别名 transferrin receptor

Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 是一种 PE-conjugated Mouse 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 可用于 FCM。

Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)

Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)

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产品编号 TMAY-01475P 别名 transferrin receptor

Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 是一种 PE-conjugated Mouse 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 可用于 FCM。

规格价格库存数量
25 T
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100 T
¥ 890
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产品介绍

生物活性
产品描述
Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) is a PE-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) can be used in FCM.
别名transferrin receptor
Ig Type
Mouse IgG1
克隆号
6G357
交叉反应
Human
特异性
Human Transferrin Receptor/TFR1/CD71
验证活性
Flow cytometric analysis of Human TFRC(CD71) expression on U937 cells. Cells were stained with PE-conjugated anti-Human TFRC(CD71). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe760) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/APC/PerCP/FITC
可提供抗体种类
5
抗原信息
免疫原
Recombinant Protein: Human Transferrin Receptor / TFRC / CD71 Protein (TMPY-01873)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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