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Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)
还可以产品编号 TMAY-01475P
Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 是一种 PE-conjugated Mouse 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 可用于 FCM。
Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)
Anti-Transferrin Receptor/TFRC Antibody-PE (6G357)
还可以产品编号 TMAY-01475P
Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 是一种 PE-conjugated Mouse 抗体，靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) is a PE-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-PE (6G357) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6G357 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human TFRC(CD71) expression on U937 cells. Cells were stained with PE-conjugated anti-Human TFRC(CD71). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe760) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/PerCP/FITC |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human Transferrin Receptor / TFRC / CD71 Protein (TMPY-01873) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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