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Anti-KIT Monoclonal Antibody (5M199) 是一种 Mouse 抗体,靶向 KIT。Anti-KIT Monoclonal Antibody (5M199) 可用于 IF,FCM。
别名 SCFR, PBT, MASTC, C-Kit, CD117
Anti-KIT Monoclonal Antibody (5M199) 是一种 Mouse 抗体,靶向 KIT。Anti-KIT Monoclonal Antibody (5M199) 可用于 IF,FCM。

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| 产品描述 | Anti-KIT Monoclonal Antibody (5M199) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (5M199) can be used in IF,FCM. |
| 别名 | SCFR, PBT, MASTC, C-Kit, CD117 |
| Ig Type | IgG2b |
| 克隆号 | 5M199 |
| 反应种属 | Human |
| 应用 | IFFCM |
| 推荐剂量 | IF: 1/50-1/200; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human KIT (AA: 23-322) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | KIT |
| 基因ID | |
| 蛋白名称 | Mast/stem cell growth factor receptor Kit |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |