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Anti-KIT Monoclonal Antibody (5M199)

Synonyms: SCFR, PBT, MASTC, C-Kit, CD117
货号 TMAT-0800 一键复制产品信息
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Anti-KIT Monoclonal Antibody (5M199) 是一种 Mouse 抗体,靶向 KIT。Anti-KIT Monoclonal Antibody (5M199) 可用于 IF,FCM。

Anti-KIT Monoclonal Antibody (5M199)

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货号 TMAT-0800

别名 SCFR, PBT, MASTC, C-Kit, CD117

Anti-KIT Monoclonal Antibody (5M199) 是一种 Mouse 抗体,靶向 KIT。Anti-KIT Monoclonal Antibody (5M199) 可用于 IF,FCM。

Anti-KIT Monoclonal Antibody (5M199)
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产品介绍


生物活性
产品描述
Anti-KIT Monoclonal Antibody (5M199) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (5M199) can be used in IF,FCM.
别名
SCFR, PBT, MASTC, C-Kit, CD117
Ig Type
IgG2b
克隆号
5M199
反应种属
Human
应用IFFCM
推荐剂量
IF: 1/50-1/200; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human KIT (AA: 23-322) expressed in E. Coli.
抗原种属
Human
基因名称
KIT
基因ID
蛋白名称
Mast/stem cell growth factor receptor Kit
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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