A 6

Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽，它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性，能通过与 CD44 结合并调节 CD44 介导的细胞信号传导，抑制肿瘤细胞的迁移、侵袭和转移。

Cucumarioside A6-2 is a triterpene glycoside.

[D-Ala6]-LH-RH，一种黄体激素释放激素(LHRH)模拟物，充当GnRH受体的激动剂。

'(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)' 为一种GnRH类似物，主要用于诱导养殖鱼类排卵和/或产卵。

[D-Phe2,D-Ala6]-LH-RH 为有效LH-RH拮抗剂，展现了显著的抗LH/FSH-RH及抗排卵活性。

Tat-CBD3A6K是一种肽类化合物，为N型电压门控钙通道Cav2.2以及collapsin response mediator protein 2 (CRMP2) 蛋白-蛋白相互作用抑制剂Tat-CBD3的衍生物。Tat-CBD3A6K (10 mg/kg) 能够阻止由d4T (stavudine)引发的大鼠抗逆转录病毒神经病痛模型中爪撤回阈值的下降，并减少同一大鼠分离的背根神经节(DRG)神经元的动作电位数量。通过硬膜途径给予Tat-CBD3A6K (30 µM/animal) 能够减少由萜类生物碱辣椒素引发的大鼠硬脑膜血流增加。

Corza6 是一种高效且针对性的人类电压门控质子通道 (hHv1) 的肽抑制剂。在哺乳动物细胞具有天然超极化静息膜电位 (RMP) 的环境下，Corza6 以Kd约为 ~1 nM 结合到 hHv1 的外部电压传感器域 (VSD) 环上。Corza6 能够促进精子获能，并维持白细胞 (WBC) 中的活性氧 (ROS) 生成。

TAT-CBD3A6K 是一种经修饰的 TAT-CBD3 肽，能够减少背根神经节 (DRG) 神经元中的 T 型和 R 型电压依赖性钙电流。通过抑制 CRMP-2 介导的 T 型和 R 型钙通道的功能增强，TAT-CBD3A6K 在 AIDS 诱导的周围神经病变模型中表现出抗伤害作用。

Corza6 TFA 是一种高效且具选择性的人类电压门控质子通道 (hHv1) 的肽抑制剂。在哺乳动物细胞天然的超极化静息膜电位 (RMP) 下，Corza6 TFA 以约 Kd 1 nM 的结合力与 hHv1 的外部电压传感器域 (VSD) 环结合。Corza6 TFA 能促进精子获得能量，并允许白细胞 (WBC) 中持续产生活性氧 (ROS)。

[D-p-Cl-Phe6,Leu17]-VIP acetate 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂 (IC50 = 125.8 nM)。

VIP(6-28)(human, rat, porcine, bovine) acetate 是外源性血管活性肠肽 (VIP) 受体对颈上神经节 (SCG) 中 cAMP 作用的拮抗剂。

PKA inhibitor fragment (6-22) amide Acetate 是一种通过结合底物位点选择性抑制PKA 活性的合成肽(IC50 < 2 nM)。

PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide production and degranulation in isolated human eosinophils when used at a concentration of 500 μM.3PAR2 (1-6) amide (5 μmol/kg) induces tear secretion in rats when used in combination with amastatin .4 1.Bohm, S.K., Kong, W., Bromme, D., et al.Molecular cloning, expression and potential functions of the human proteinase-activated receptor-2Biochem. J.314(Pt 3)1009-1016(1996) 2.Kanke, T., Ishiwata, H., Kabeya, M., et al.Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2Br. J. Pharmacol.145(2)255-263(2005) 3.Miike, S., McWilliam, A.S., and Kita, H.Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2J. Immunol.167(11)6615-6622(2001) 4.Nishikawa, H., Kawai, K., Tanaka, M., et al.Protease-activated receptor-2 (PAR-2)-related peptides induce tear secretion in rats: Involvement of PAR-2 and non-PAR-2 mechanismsJ. Pharmacol. Exp. Ther.312(2)324-331(2005)

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1].

Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expressed in CHO cells. It binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively) and inhibits cAMP accumulation induced by PACAP (1-38) (Kis = 457, 102, and 283 nM, respectively, in SH-SY5Y, SK-N-MC, and T47D cells). In vivo, in newborn pigs, PACAP (6-27) (10 μM) inhibits vasodilation of pial arterioles induced by PACAP (1-27) and PACAP (1-38) . It also inhibits PACAP (1-27)-stimulated increases in plasma insulin and glucagon levels and pancreatic venous blood flow in dogs when administered locally to the pancreas at a dose of 500 μg.

PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth in the presence and absence of growth factors. PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.

Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angiotensin I is then hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.

TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。

TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.

Mad1 (6-21) is a peptide fragment derived from the Mad1 protein, specifically encompassing residues 6 to 21. This fragment exhibits binding affinity towards the mammalian Sin3A PAH2 domain, with a Kd value of approximately 29 nM.

(S)-Methyl 6-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)hexanoate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64462，CAS号为 73548-77-3。

(S)-2-Amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64848，CAS号为 1155-64-2。

(S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64941，CAS号为 33468-35-8。