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别名 Yervoy
Anti-Ipilimumab Antibody (6H77) 是一种 Mouse 抗体,靶向 Ipilimumab。Anti-Ipilimumab Antibody (6H77) 可用于 ELISA。
Anti-Ipilimumab Antibody (6H77) 是一种 Mouse 抗体,靶向 Ipilimumab。Anti-Ipilimumab Antibody (6H77) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 40 μg | ¥ 1,609 | 5日内发货 |
| 产品描述 | Anti-Ipilimumab Antibody (6H77) is a Mouse antibody targeting Ipilimumab. Anti-Ipilimumab Antibody (6H77) can be used in ELISA. |
| 别名 | Yervoy |
| Ig Type | IgG1 |
| 克隆号 | 6H77 |
| 特异性 | The product is specific for Ipilimumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody Anti-Ipilimumab Antibody (9Z335) (TMAS-00048). |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.01-0.1 µg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 纯化方式 | Protein A affinity column |
| 性状 | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| 缓冲液 | Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| 研究背景 | Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Biotin |
| 可提供抗体种类 | 2 |
| 免疫原 | Ipilimumab |
| 储存方式 | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | -20°C for 1 year |