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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody

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货号 TMAB-11199

Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PTPN6 (Tyr536)。Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody

Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11199

Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PTPN6 (Tyr536)。Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN6 (Tyr536). Anti-Phospho-PTPN6 (Tyr536) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human (predicted:Dog,Horse)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II. Shuttles between the cytoplasm and nucleus via its association with PDPK1.
组织特异性Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human PTPN6 around the phosphorylation site of Tyr536
抗原种属
Human
基因名称
PTPN6
基因ID
5777
蛋白名称
Tyrosine-protein phosphatase non-receptor type 6
Uniprot ID
P29350
功能
Modulates signaling by tyrosine phosphorylated cellcsurface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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