规格

价格

库存

数量

1 mg

¥ 1,160

现货

5 mg

¥ 2,880

现货

10 mg

¥ 4,480

现货

25 mg

¥ 6,960

现货

50 mg

¥ 9,380

现货

生物活性

产品描述	Kushenol I is a bioactive compound exhibiting anti-inflammatory, antioxidant, and ulcerative colitis–ameliorating effects, demonstrated in a DSS-induced UC mouse model where oral administration improved colon length, body weight, and disease scores while reducing pro-inflammatory cytokines including IL-1β, IL-6, IL-17, and TNF-α. Kushenol I increase IL-10 expression, inhibited key inflammatory signaling proteins such as AKT, p38 MAPK, PI3K, NLRP3, FOXO1, and TLR4, enhancing intestinal barrier integrity. Kushenol I positively modulate gut microbiota, and elevated splenic T-cell proportions, supporting therapeutic potential in inflammatory bowel disease.
体外活性	新化合物2-methoxyanofinic acid、其甲酯化物、苦参素及Kushenol I对植物病原真菌Cladosporium cucumerinum具有活性[1]。
别名	苦参醇 I

化学信息

分子量	454.51
分子式	C₂₆H₃₀O₇
CAS No.	99119-69-4
Smiles	C([C@@H](CC=C(C)C)C(C)=C)C1=C2C(=C(OC)C=C1O)C(=O)[C@H](O)[C@H](O2)C3=C(O)C=C(O)C=C3
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 80 mg/mL (176.01 mM), Sonication is recommeded.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2002 mL	11.0009 mL	22.0017 mL	110.0086 mL
5 mM	0.4400 mL	2.2002 mL	4.4003 mL	22.0017 mL
10 mM	0.2200 mL	1.1001 mL	2.2002 mL	11.0009 mL
20 mM	0.1100 mL	0.5500 mL	1.1001 mL	5.5004 mL
50 mM	0.0440 mL	0.2200 mL	0.4400 mL	2.2002 mL
100 mM	0.0220 mL	0.1100 mL	0.2200 mL	1.1001 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Kushenol I

Kushenol I

产品介绍

引用文献

计算器

体内实验配液计算器

剂量转换

关键词

Kushenol I

Kushenol I

Kushenol I 相关产品

产品介绍

引用文献

计算器

体内实验配液计算器

剂量转换

关键词