购物车
- 全部删除
- 您的购物车当前为空
Anti-SHH Antibody (6B515) 是一种 Mouse 抗体,靶向 SHH。Anti-SHH Antibody (6B515) 可用于 ELISA。
Anti-SHH Antibody (6B515) 是一种 Mouse 抗体,靶向 SHH。Anti-SHH Antibody (6B515) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 1,679 | 5日内发货 |
产品描述 | Anti-SHH Antibody (6B515) is a Mouse antibody targeting SHH. Anti-SHH Antibody (6B515) can be used in ELISA. |
别名 | sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 6B515 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SHH / Sonic hedgehog (rh SHH / Sonic hedgehog; TMPY-02832; Q15465; Met1-Gly197). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein that is vital in guiding the early embryo. It has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Sonic HedgeHog intercellular signal is essential for a various patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Sonic HedgeHog binds to the patched receptor, which functions in association with smoothened, to activate the transcription of target genes. In the absence of sonic HedgeHog, patched receptor represses the constitutive signaling activity of smoothened. Sonic HedgeHog also regulates another factor, the gli oncogene. Defects in sonic hedgehog can cause microphthalmia isolated with coloboma type 5, triphalangeal thumb-polysyndactyly syndrome and holoprosencephaly type 3. |
偶联 | Unconjugated |
免疫原 | Recombinant Human SHH / Sonic hedgehog Protein (TMPY-02832) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容