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Anti-SHH Antibody (6B515)

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产品编号 TMAY-00714
别名 sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik

Anti-SHH Antibody (6B515) 是一种 Mouse 抗体,靶向 SHH。Anti-SHH Antibody (6B515) 可用于 ELISA。

Anti-SHH Antibody (6B515)

Anti-SHH Antibody (6B515)

Rating icon 还可以
产品编号 TMAY-00714 别名 sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik

Anti-SHH Antibody (6B515) 是一种 Mouse 抗体,靶向 SHH。Anti-SHH Antibody (6B515) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-SHH Antibody (6B515) is a Mouse antibody targeting SHH. Anti-SHH Antibody (6B515) can be used in ELISA.
别名sonic hedgehog, M100081, Hxl3, Hx, Hhg1, Dsh, 9530036O11Rik
Ig Type
Monoclonal Mouse IgG1
克隆号
6B515
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SHH / Sonic hedgehog (rh SHH / Sonic hedgehog; TMPY-02832; Q15465; Met1-Gly197). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Sonic HedgeHog, also known as sonic hedgehog protein, belongs to the hedgehog family. It cannot be detected in adult tissues while can be found in fetal intestine, liver, lung, and kidney. Sonic HedgeHog is a protein that is vital in guiding the early embryo. It has been associated as the major inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Sonic HedgeHog intercellular signal is essential for a various patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Sonic HedgeHog binds to the patched receptor, which functions in association with smoothened, to activate the transcription of target genes. In the absence of sonic HedgeHog, patched receptor represses the constitutive signaling activity of smoothened. Sonic HedgeHog also regulates another factor, the gli oncogene. Defects in sonic hedgehog can cause microphthalmia isolated with coloboma type 5, triphalangeal thumb-polysyndactyly syndrome and holoprosencephaly type 3.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human SHH / Sonic hedgehog Protein (TMPY-02832)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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