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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SMC6 Polyclonal Antibody

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货号 TMAB-12968

Anti-SMC6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SMC6。Anti-SMC6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SMC6 Polyclonal Antibody

Anti-SMC6 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12968

Anti-SMC6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SMC6。Anti-SMC6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-SMC6 Polyclonal Antibody is a Rabbit antibody targeting SMC6. Anti-SMC6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Widely expressed. Overexpressed in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SMC6
抗原种属
Human
基因名称
SMC6
基因ID
79677
蛋白名称
Structural maintenance of chromosomes protein 6
功能
Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies.
化学信息
分子量Theoretical: 126 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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