规格

价格

库存

数量

1 mg

¥ 295

现货

5 mg

¥ 695

现货

10 mg

¥ 1,090

现货

25 mg

¥ 1,980

现货

50 mg

¥ 3,290

现货

100 mg

¥ 4,730

现货

1 mL x 10 mM (in DMSO)

¥ 765

现货

生物活性

产品描述	ZQ-16 is a potent and highly selective agonist for the G protein-coupled receptor GPR84, demonstrating a half-maximal effective concentration (EC50) of 0.213 μM, and it activates multiple downstream signaling pathways including calcium mobilization, inhibition of cAMP accumulation, phosphorylation of extracellular signal-regulated protein kinase 1/2 (ERK1/2), receptor desensitization and internalization, and receptor-β-arrestin interaction, making it a useful tool compound for studying GPR84 function and a candidate for further optimization.
体外活性	ZQ-16（10 μM，5 分钟）处理表达 GPR84 的 HEK293 细胞，能诱导细胞中的 ERK1/2 的磷酸化。[1]
别名	ZQ16

化学信息

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 20 mg/mL (87.6 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (8.76 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO