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Anti-Ube2L6 Polyclonal Antibody

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货号 TMAB-13939

Anti-Ube2L6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Ube2L6。Anti-Ube2L6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Ube2L6 Polyclonal Antibody

Anti-Ube2L6 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13939

Anti-Ube2L6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Ube2L6。Anti-Ube2L6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Ube2L6 Polyclonal Antibody is a Rabbit antibody targeting Ube2L6. Anti-Ube2L6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Present in natural killer cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells, either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. Ubiquitin conjugating enzyme 8 (UBC8) is an E2 enzyme involved in the ubiquitin pathway for protein degradation. Like other E2 enzymes, UBC8 forms a thioester bond with ubiquitin in an E1-dependent manner. UBC8 binds to the human homolog of Drosophila ariadne (HHARI) and UBC7-associated protein (H7-AP1) as well as double ring-finger protein (Dorfin). UBC8 is enriched in the central nervous system and interacts with Parkin, a RING-finger-containing protein implicated in the pathogenesis of familial Parkinson’s disease. Parkin shares sequence homology with other UBC8 binding proteins such as HHARI and H7-AP1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ube2L6
抗原种属
Human
基因名称
UBE2L6
基因ID
蛋白名称
Ubiquitin/ISG15-conjugating enzyme E2 L6
Uniprot ID
功能
Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
化学信息
分子量Theoretical: 18 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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