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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RAB21 Antibody (6K181)

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货号 TMAB-11984

Anti-RAB21 Antibody (6K181) 是一种 Mouse 抗体，靶向 RAB21。Anti-RAB21 Antibody (6K181) 可用于 WB。

Anti-RAB21 Antibody (6K181)

Anti-RAB21 Antibody (6K181)

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Rating icon 还可以
货号 TMAB-11984

Anti-RAB21 Antibody (6K181) 是一种 Mouse 抗体，靶向 RAB21。Anti-RAB21 Antibody (6K181) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-RAB21 Antibody (6K181) is a Mouse antibody targeting RAB21. Anti-RAB21 Antibody (6K181) can be used in WB.
Ig Type
IgG2b,k
克隆号
6K181
反应种属
Human,African Green Monkey (predicted:Monkey)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane. Cleavage furrow. Note=In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid-telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells.
组织特异性Widely expressed. In jejunal tissue, predominantly expressed in the apical region of the epithelial cell layer of the villi, weak expression, if any, in the crypt epithelium. Capillary endothelium and some cell types in the lamina propria also show expression.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]
抗原信息
免疫原
Recombinant Protein: human RAB21 between 1-225 amino acids
抗原种属
Human
基因名称
RAB21
基因ID
23011
蛋白名称
Ras-related protein Rab-21
Uniprot ID
Q9UL25
功能
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis.
化学信息
分子量Theoretical: 24 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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