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顶部产品介绍化学信息储存和溶解信息计算器

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

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纯度: 98.9%

货号 T77598Cas号 906258-69-3

别名 (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) 是一种生物合成的原材料，可用于合成多种化合物。

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine
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Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine

一键复制产品信息
Rating icon 很棒

纯度: 98.9%

货号 T77598 别名 (4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanoneCas号 906258-69-3

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) 是一种生物合成的原材料，可用于合成多种化合物。

规格价格库存数量
1 mg
¥ 209
现货
5 mg
¥ 517
现货
10 mg
¥ 826
现货
25 mg
¥ 1,790
现货
50 mg
¥ 2,500
现货
100 mg
¥ 3,450
现货
200 mg
¥ 4,530
现货
1 mL x 10 mM (in DMSO)
¥ 571
现货
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纯度: 98.9%
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产品介绍

Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine AI Summary
Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine exhibits multifaceted bioactivities, functioning prominently as an inhibitor and modulator across various biochemical pathways. It acts as a modulator of miRNAs and an activator/inhibitor of miR-21 with a potency of 8260.4 nM and inhibits Tau fibril formation with a Thioflavin T binding potency of 15848.9 nM. Additionally, it effectively inhibits the Nrf2 pathway with a potency of 4610.9 nM, Histone Lysine Methyltransferase G9a at 3548.1 nM, and BAZ2B at 22387.2 nM. The compound also suppresses Polymerase Iota at 89125.1 nM, Lassa Virus binding/entry at 1584.9 nM, and ATXN expression at 39810.7 nM while activating BRCA1 expression with a potency of 1584.9 nM. It inhibits human tyrosyl-DNA phosphodiesterase 1 (TDP1) with potencies of 29092.9 nM (absence of CPT) and 23109.3 nM (presence of CPT) and shows inhibitory activity against PTHR with a potency of 125892.5 nM. Moreover, Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine is a potent inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 2840.0 nM and achieving 89.8% inhibition at 33.33 µM relative to the control. Surface plasmon resonance (SPR) analysis reveals a binding affinity (Kd) to MAGL of 710.0 nM. Additionally, it shows inhibitory/activator effects on firefly luciferase with a potency of 19011.5 nM..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Anisole-piperazine-methanone-benzothiazole-p-methylpiperidine ((4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone) is a raw material for biosynthesis and can be used to synthesize a wide variety of compounds.
别名(4-(4-methoxyphenyl)piperazin-1-yl)(2-(4-methylpiperidin-1-yl)benzo[d]thiazol-6-yl)methanone
化学信息
分子量450.6
分子式C25H30N4O2S
CAS No.906258-69-3
SmilesC(=O)(C=1C=C2C(N=C(S2)N3CCC(C)CC3)=CC1)N4CCN(CC4)C5=CC=C(OC)C=C5
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 15 mg/mL (33.29 mM), Sonication and heating to 60℃ are recommended.
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM2.2193 mL11.0963 mL22.1926 mL110.9632 mL
5 mM0.4439 mL2.2193 mL4.4385 mL22.1926 mL
10 mM0.2219 mL1.1096 mL2.2193 mL11.0963 mL
20 mM0.1110 mL0.5548 mL1.1096 mL5.5482 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
TargetMol | Animal experiments 比如您的给药剂量是10 mg/kg，每只动物体重20g，给药体积100 μL， TargetMol | Animal experiments 一共给药动物10只，您使用的配方为5%TargetMol | reagent DMSO + 30%PEG300 + 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为2mg/mL。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween80, 混匀澄清，再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO ， PEG300 / PEG400 ， Tween 80 ， SBE-β-CD ， 玉米油 等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

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