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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RBBP6 Polyclonal Antibody

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货号 TMAB-12128

Anti-RBBP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RBBP6。Anti-RBBP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RBBP6 Polyclonal Antibody

Anti-RBBP6 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12128

Anti-RBBP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RBBP6。Anti-RBBP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-RBBP6 Polyclonal Antibody is a Rabbit antibody targeting RBBP6. Anti-RBBP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleolus. Chromosome. Cytoplasm, cytoskeleton, centrosome. Note=Colocalizes with mitotic chromosomes. Co-localizes with NEK6 in the centrosome.
组织特异性Highly expressed in the placenta and testis. Expressed at lower levels in the brain, heart, kidney, liver and lung. Overexpressed in esophageal cancer.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景he retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human RBBP6
抗原种属
Human
基因名称
RBBP6
基因ID
5930
蛋白名称
E3 ubiquitin-protein ligase RBBP6
Uniprot ID
Q7Z6E9
功能
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
化学信息
分子量Theoretical: 201 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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