gr

NXT629 是一种具有选择性和高效性的 PPAR-α 拮抗剂，具有抗癌活性，抑制 PPARδ，PPARγ，Erβ，GR 和 TRβ，可用于研究卵巢癌和黑色素瘤。

OP-3633 is an effective and selective steroidal glucocorticoid receptor (GR) antagonist (IC50: 29 nM). OP-3633 shows low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism. It also has an inhibition of GR transcriptional activity.

Exicorilant is a selective and oral active glucocorticoid receptor (GR) antagonist (Ki: 7 nM) and it also has the potential to overcome adiposity, glucose intolerance, and dyslipidemia.

GR-95168 ((+)-C-BVDU) 是一种抗病毒化合物，可用于研究1型和2型单纯疱疹病毒感染。

GR 103691 是选择性的多巴胺 D3受体拮抗剂，Ki=0.4 nM。它对人多巴胺 D3的选择性超过 D4和 D1的 100 倍以上。

GR 113808 是一种具有选择性的 5-HT4 receptor 拮抗剂，抑制 5-HT1B，5-HT2A，5-HT2C 和 5-HT3 受体，可减弱多巴胺释放。

GR 159897 is a competitive, brain-penetrated non-peptide NK2 receptor antagonist with anti-tumor effects. GR 159897 inhibits binding of [3H]GR100679 to human NK2-CHO cells and rat colon membranes (pKis: 9.51 and 10, respectively). It can antagonize bronch

GR148672X 是三酰甘油水解酶抑制剂(IC50:4 nM)。

GR-14-3-3 stabilizer-1 (compound 10) 是一种分子胶稳定剂，专门用于制备靶向糖皮质激素 (GR) 的分子胶，阻碍 GR 与 14-3-3 的相互作用。

GR 125487 sulfamate is a 5-HT4 receptor antagonist.

5-HT1B 1D receptor antagonist

platelet fibrinogen receptor glycoprotein IIb IIIa (GpIIb IIIa) antagonist

5-HT1B (5-HT1Dβ) silent antagonist

GR 89696 fumarate 是一种高效选择性的κ2 opioid receptor 受体激动剂(IC50 = 0.04 nM)，具有预防瘙痒、体内抗伤害和神经保护作用。

Potent and selective tachykinin NK2 receptor antagonist

GR 94800 acetate 是一种有效的选择性神经激肽 2(NK-2) 拮抗剂。

GR 122222X is an inhibitor of topoisomerase II.

GR-125487 is a 5-HT4R partial agonist. It also has favorable ADME properties and good in vivo efficacy.

GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR-203040 is a selective NK1 receptor antagonist.

GR 100679 is an antagonist of NK2 receptor.

GR 128107 is an antagonist of melatonin receptor.

GR 196429, a melatonin receptor agonist, exhibits selectivity for the MT1 subtype. This compound not only promotes sleep and alters circadian rhythms but also stimulates melatonin release in mice.

GR 218,231 is a selective antagonist of D3 dopamine receptor.

GR 175737 is a bioactive chemical.