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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-GRIA2 Monoclonal Antibody (5X785)

Synonyms: HBGR2, GluR-K2, GLURB, GLUR2, GluA2
货号 TMAT-1028 一键复制产品信息
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Anti-GRIA2 Monoclonal Antibody (5X785) 是一种 Mouse 抗体，靶向 GRIA2。Anti-GRIA2 Monoclonal Antibody (5X785) 可用于 IHC,FCM。

Anti-GRIA2 Monoclonal Antibody (5X785)

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Rating icon 还可以
货号 TMAT-1028

别名 HBGR2, GluR-K2, GLURB, GLUR2, GluA2

Anti-GRIA2 Monoclonal Antibody (5X785) 是一种 Mouse 抗体，靶向 GRIA2。Anti-GRIA2 Monoclonal Antibody (5X785) 可用于 IHC,FCM。

Anti-GRIA2 Monoclonal Antibody (5X785)
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产品介绍

生物活性
产品描述
Anti-GRIA2 Monoclonal Antibody (5X785) is a Mouse antibody targeting GRIA2. Anti-GRIA2 Monoclonal Antibody (5X785) can be used in IHC,FCM.
别名
HBGR2, GluR-K2, GLURB, GLUR2, GluA2
Ig Type
IgG2b
克隆号
5X785
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/mL
研究背景Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human GRIA2 (AA: 35-175) expressed in E. Coli.
抗原种属
Human
基因名称
GRIA2
基因ID
2891
蛋白名称
Glutamate receptor 2
Uniprot ID
P42262
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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