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抑制剂 & 化合物

802

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化合物库

1336

重组蛋白

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Cat. No.	Product Name
L2150	抗癌药物库		3159 compounds
	3159 个具有抗癌活性小分子的独特集合，生物活性已经临床前实验证实，可用于高通量、高内涵筛选；
L2190	抗肺癌化合物库		1735 compounds
	1735 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L2100	抗癌化合物库		7360 compounds
	7360 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2192	抗胰腺癌化合物库		2267 compounds
	2267 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；
L2120	抗癌临床化合物库		2614 compounds
	2614 个具有抗癌活性小分子的独特集合，可用于高通量高内涵筛选。
L2180	抗肿瘤库Plus		1468 compounds
	1468 种抗肿瘤相关、结构新颖的化合物；
L2191	抗乳腺癌化合物库		1965 compounds
	1965 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L2140	癌细胞分化化合物库		413 compounds
	413 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2160	抗癌活性化合物库		3250 compounds
	3250 种具有抗肿瘤活性的化合物的特有集合，用于高通量、高内涵筛选；
L2130	抗癌细胞代谢库		1280 compounds
	1280 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L2110	抗癌上市药物库		1825 compounds
	1825 个具有抗癌活性小分子的独特集合，所有化合物都经过了严格的临床前研究和临床试验，由FDA、EMA 或NMPA 批准上市，可用于高通量、高内涵筛选。
L2195	抗前列腺癌化合物库		2096 compounds
	2096 种与前列腺癌相关的化合物，可以用于高通量和高内涵筛选
L2193	抗肝癌化合物库		1816 compounds
	1816 种与肝癌相关的化合物，可以用于抗肝癌药物研发和药理研究；
L2194	抗结直肠癌化合物库		1565 compounds
	1565 种与结直肠癌相关的化合物，可以用于高通量和高内涵筛选；
L2196	抗卵巢癌化合物库		1888 compounds
	1888 种与卵巢癌相关的化合物，可以用于抗卵巢癌药物研发和药理研究
L6740	抗结直肠癌中药单体化合物库		386 compounds
	386 种抗结直肠癌相关的中药单体集合，是药物开发、药理研究的有效工具；
L2170	肿瘤免疫治疗小分子化合物库		454 compounds
	454 种靶向肿瘤免疫治疗靶点的小分子，可用于高通量和高内涵筛选，是研究肿瘤免疫治疗的有力工具；
L2501	人内源代谢化合物库 Plus		1300 compounds
	1300种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L2520	糖代谢化合物库		708 compounds
	708 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L4300	Wnt/Hedgehog/Notch 通路化合物库		240 compounds
	240 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合，用于相关通路的研究及药物的筛选，可用于高通量、高内涵筛选。
L3900	DNA 损伤和修复分子库		937 compounds
	937 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
L4800	血管生成库		1370 compounds
	1370 个高潜力的抑制或促进血管生成的小分子集合，可用于药物靶点开发、血管生成机理研究的高通量筛选，高内涵筛选；
L9420	外泌体相关化合物库		80 compounds
	80 种外泌体相关的化合物，可以用于高通量和高内涵筛选；
L2152	靶向治疗药物库		121 compounds
	121 个肿瘤靶向治疗药物，可以用于高通量和高内涵筛选；
L6100	天然多酚类化合物库		640 compounds
	640 个天然多酚化合物的独特集合，可用于高通量、高内涵筛选；
L3980	DNA损伤/修复库Plus		667 compounds
	667 种 DNA 损伤/修复靶向、结构新颖的化合物；
L1200	表观遗传库		960 compounds
	960 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；
L6700	抗癌天然产物库		1800 compounds
	1800 种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS 和HCS。
L9000	细胞凋亡化合物库		1796 compounds
	1796 种与凋亡相关的生物活性小分子化合物的特有集合，多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选；
L8710	铜死亡化合物库		411 compounds
	TargetMol 铜死亡化合物库集合了 411 种与铜死亡相关的化合物，可以用于铜死亡机制及相关疾病研究
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L3510	甲基化化合物库		131 compounds
	131 种甲基化相关的化合物，可以用于高通量和高内涵筛选；
L2550	谷氨酰胺代谢化合物库		580 compounds
	580 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；
L6110	生物碱类天然产物库		468 compounds
	468 种生物碱类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L5200	抗代谢疾病化合物库		1558 compounds
	1558 个代谢疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6200	瑶药化合物库		225 compounds
	225 种瑶药来源的天然产物分子集合，可以用于高通量和高内涵筛选；
L1300	PI3K/Akt/mTOR 化合物库		425 compounds
	425 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；
L1100	蛋白酶抑制剂库		344 compounds
	344 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L3400	临床期小分子药物库		3480 compounds
	3480 个临床期化合物集合，可用于高通量筛选和高内涵筛选；
L2510	脂代谢化合物库		496 compounds
	496 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L2910	抗氧化化合物库		1330 compounds
	氧化应激（Oxidative Stress，OS）是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧（ROS）大量积累，氧化程度超出抗氧化物的清除能力，从而引起氧化损伤，氧化应激损伤是许多疾病发生的基础，不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激，降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1330 种对氧化应激具有抑制作用的小分子特有集合，是研究氧化应激的有用工具，可以用于高通量筛选和高内涵筛选。
L2151	化疗药物库		51 compounds
	51 个肿瘤化疗药物，可以用于高通量和高内涵筛选；
L9400	PPI抑制剂库		490 compounds
	490 种已知活性的 PPI 相关的抑制剂，可用于高通量、高内涵筛选；
L2000	抑制剂库		8418 compounds
	8418 个小分子抑制剂的独特集合，主要用于细胞信号研究、新药筛选、高通量筛选和高内涵筛选；
L8500	HIF-1化合物库		1352 compounds
	1352 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
L6130	萜类天然产物库		522 compounds
	522 种萜类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L1610	FDA 上市激酶抑制剂库		266 compounds
	266种靶向激酶的上市药物集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L2521	糖酵解化合物库		560 compounds
	560 种糖酵解相关的活性化合物，可用于高通量和高内涵筛选
L8700	铁死亡化合物库		800 compounds
	800 种与铁死亡通路相关的化合物，可用于高通量和高内涵筛选；
L8600	泛素化化合物库		214 compounds
	214 种泛素化相关的小分子，用于高通量和高内涵筛选；
L8300	染色质修饰分子库		256 compounds
	256 种染色质化学修饰相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2010	高选择性抑制剂库		580 compounds
	xunm种具有高选择性的抑制剂集合
L6600	胃肠炎天然产物库		223 compounds
	223 种胃肠炎相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L8100	细胞周期化合物库		695 compounds
	695 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L8400	血液病分子库		524 compounds
	524 种造血系统疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L2500	人内源代谢化合物库		508 compounds
	508 种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
L2560	代谢化合物库		2350 compounds
	2350 种代谢途径相关的化合物，可用于高通量和高内涵筛选。
L8720	细胞焦亡化合物库		1077 compounds
	1077 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。
L6120	黄酮类天然产物库		477 compounds
	477 种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L9600	多肽分子库		800 compounds
	800 种多肽类分子，可用于多肽药物开发及信号转导通路和作用机制研究；
L5300	线粒体靶向库		830 compounds
	830 种具有潜在或确定线粒体靶向活性的化合物，以促进针对线粒体的药物研究；
L1310	细胞骨架化合物库		773 compounds
	773 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；
L4600	植物来源化合物库		3076 compounds
	3076 个植物来源天然产物的独特集合，来自277类植物的精心之选；
L5510	肝脏毒性化合物库		1040 compounds
	1040 个肝脏毒性化合物的特有集合，可用于高通量、高内涵筛选，是毒理学研究的良好工具；
L6810	中药单体化合物库		2771 compounds
	2771 种中药来源的单体化合物，是药物开发、药理研究等领域的有力工具；
L6500	微生物天然产物库		560 compounds
	560 种微生物来源的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L9410	共价抑制剂库		1949 compounds
	1949 种小分子的独特集合，包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子，如氯乙酰基，2-氯丙酰基，丙烯酰基，1-丙-2-炔基，1-丁-2-炔基，酮羰基，二硫键等，可以用于共价抑制剂药物研发；

化合物库

抗癌药物库

Cat.No: L2150

Compounds: 3159

抗肺癌化合物库

Cat.No: L2190

Compounds: 1735

抗癌化合物库

Cat.No: L2100

Compounds: 7360

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2267

抗癌临床化合物库

Cat.No: L2120

Compounds: 2614

抗肿瘤库Plus

Cat.No: L2180

Compounds: 1468

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1965

癌细胞分化化合物库

Cat.No: L2140

Compounds: 413

抗癌活性化合物库

Cat.No: L2160

Compounds: 3250

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1280

抗癌上市药物库

Cat.No: L2110

Compounds: 1825

抗前列腺癌化合物库

Cat.No: L2195

Compounds: 2096

抗肝癌化合物库

Cat.No: L2193

Compounds: 1816

抗结直肠癌化合物库

Cat.No: L2194

Compounds: 1565

抗卵巢癌化合物库

Cat.No: L2196

Compounds: 1888

抗结直肠癌中药单体化合物库

Cat.No: L6740

Compounds: 386

肿瘤免疫治疗小分子化合物库

Cat.No: L2170

Compounds: 454

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1300

糖代谢化合物库

Cat.No: L2520

Compounds: 708

Wnt/Hedgehog/Notch 通路化合物库

Cat.No: L4300

Compounds: 240

DNA 损伤和修复分子库

Cat.No: L3900

Compounds: 937

血管生成库

Cat.No: L4800

Compounds: 1370

外泌体相关化合物库

Cat.No: L9420

Compounds: 80

靶向治疗药物库

Cat.No: L2152

Compounds: 121

天然多酚类化合物库

Cat.No: L6100

Compounds: 640

DNA损伤/修复库Plus

Cat.No: L3980

Compounds: 667

表观遗传库

Cat.No: L1200

Compounds: 960

抗癌天然产物库

Cat.No: L6700

Compounds: 1800

细胞凋亡化合物库

Cat.No: L9000

Compounds: 1796

铜死亡化合物库

Cat.No: L8710

Compounds: 411

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

甲基化化合物库

Cat.No: L3510

Compounds: 131

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 580

生物碱类天然产物库

Cat.No: L6110

Compounds: 468

抗代谢疾病化合物库

Cat.No: L5200

Compounds: 1558

瑶药化合物库

Cat.No: L6200

Compounds: 225

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 425

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 344

临床期小分子药物库

Cat.No: L3400

Compounds: 3480

脂代谢化合物库

Cat.No: L2510

Compounds: 496

抗氧化化合物库

Cat.No: L2910

Compounds: 1330

化疗药物库

Cat.No: L2151

Compounds: 51

PPI抑制剂库

Cat.No: L9400

Compounds: 490

Cat.No: L2000

Compounds: 8418

HIF-1化合物库

Cat.No: L8500

Compounds: 1352

萜类天然产物库

Cat.No: L6130

Compounds: 522

FDA 上市激酶抑制剂库

Cat.No: L1610

Compounds: 266

糖酵解化合物库

Cat.No: L2521

Compounds: 560

铁死亡化合物库

Cat.No: L8700

Compounds: 800

泛素化化合物库

Cat.No: L8600

Compounds: 214

染色质修饰分子库

Cat.No: L8300

Compounds: 256

高选择性抑制剂库

Cat.No: L2010

Compounds: 580

胃肠炎天然产物库

Cat.No: L6600

Compounds: 223

细胞周期化合物库

Cat.No: L8100

Compounds: 695

血液病分子库

Cat.No: L8400

Compounds: 524

人内源代谢化合物库

Cat.No: L2500

Compounds: 508

代谢化合物库

Cat.No: L2560

Compounds: 2350

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1077

黄酮类天然产物库

Cat.No: L6120

Compounds: 477

多肽分子库

Cat.No: L9600

Compounds: 800

线粒体靶向库

Cat.No: L5300

Compounds: 830

细胞骨架化合物库

Cat.No: L1310

Compounds: 773

植物来源化合物库

Cat.No: L4600

Compounds: 3076

肝脏毒性化合物库

Cat.No: L5510

Compounds: 1040

中药单体化合物库

Cat.No: L6810

Compounds: 2771

微生物天然产物库

Cat.No: L6500

Compounds: 560

共价抑制剂库

Cat.No: L9410

Compounds: 1949

Cat. No.	Product Name	Target	Signaling Pathways
T13572	Cancer-Targeting Compound 1	Others	Others
	Cancer-Targeting Compound 1可用于激素相关癌症的研究，包括治疗或预防肌瘤、子宫平滑肌瘤、多囊卵巢综合征或激素依赖性癌等等。
T83892	33-BCRP Inhibitor 33-Breast Cancer Resistance Protein Inhibitor
	33-BCRP抑制剂是一种乳腺癌耐药蛋白(BCRP)的抑制剂。它使得对米托蒽醌耐药的H460/MX20肺癌细胞对米托蒽醌诱导的细胞死亡更加敏感，无论是单独使用还是与UV辐射联合使用。33-BCRP抑制剂还能够增强表达P-糖蛋白(P-gp，亦称为多药耐药蛋白MDR)的KB-C2表皮癌细胞对秋水仙碱诱导的细胞死亡的敏感性。当使用5 µM浓度时，它能增加米托蒽醌在H460/MX20细胞中的细胞内积累。
T22336	Galloflavin	Dehydrogenase	Metabolism
	Galloflavin 是乳酸脱氢酶抑制剂。用 Pyruvate 法得到的 Ki 为 5.46 µM (LDH-A) 以及15.06 µM (LDH-B)。它能够阻断 ATP 的生成和糖酵解，从而抑制癌细胞的增殖。
T9929	Ramucirumab	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Ramucirumab 是一种人 VEGFR-2 拮抗剂，具有抗实体瘤活性。它是人源化单克隆抗体，能够与 VEGFR-2 结合，阻碍 VEGFR 配体 VEGF-A，VEGF-C 和 VEGF-D 结合。
T2455	PFK-015 PFK15,PFK 015	Glucokinase; Autophagy	Autophagy; Metabolism
	PFK-015 (PFK15) 是一种有效的 PFKFB3 抑制剂，对重组PFKFB3的IC50为110 nM。它能抑制 Y 细胞中的 PFKFB3 活性，IC50为20 nM。
T9552	BAZ1A-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	BAZ1A-IN-1 是BAZ1A（含溴结构域蛋白）抑制剂(Kd:0.52 μM)。它对低表达BAZ1A 的癌细胞表现出弱活性或无活性，但对高表达BAZ1A 的癌细胞系显示出良好的抗生存作用。
T8432	ASP4132	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	ASP4132 是一种口服活性的 AMPK 激活剂，EC50为 18 nM，具有抗癌活性。
T2325	Neratinib HKI-272,来那替尼	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Neratinib (HKI-272) 是一种口服的、不可逆的酪氨酸激酶抑制剂，对 HER2 和 EGFR 的 IC50值分别为 59 和 92 nM。
T60028	MM41	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	MM41 是一种人类端粒和基因启动子 DNA 四链体稳定剂，对 MIA PaCa-2 胰腺癌细胞系的 IC50 <10 nM。
T9963	MPT0B390	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MPT0B390 是 HDAC 抑制剂和 TIMP3 诱导剂，可抑制肿瘤生长、转移和血管生成。
T1394	Ibuprofen Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil	COX	Immunology/Inflammation; Neuroscience
	Ibuprofen (Advil) 是一种丙酸衍生物和非甾体抗炎药 (NSAID)，具有抗炎、镇痛和解热作用。它是COX-1和COX-2的抑制剂，IC50值分别为 13 和 370 μM，导致前列腺素和血栓素前体的形成减少。
T6540	Ibuprofen Lysine 布洛芬赖氨酸盐,Neoprofen	COX	Immunology/Inflammation; Neuroscience
	Ibuprofen Lysine (Neoprofen) 是一种非甾体抗炎药。
T22263	Bavdegalutamide ARV-110	Androgen Receptor	Endocrinology/Hormones
	Bavdegalutamide (ARV-110) 是一种雄激素受体 (AR) 的 PROTAC 降解剂。 Bavdegalutamide 可用于前列腺癌的研究。 Bavdegalutamide 具有口服活性和选择性，并促进 AR 的泛素化和降解。
T6816	DASA-58	PKM	Metabolism
	DASA58 是一种有效的丙酮酸激酶M2 (PKM2) 活化剂，其中AC90=680 nM，AC50=38 nM。
T8973	HS-1793	Others	Others
	HS-1793 是 resveratrol 类似物，可以诱导细胞凋亡，在多种癌细胞中有抗肿瘤的能力。
T17258	WRG-28	Discoidin Domain Receptor (DDR)	Tyrosine Kinase/Adaptors
	WRG-28 是一种选择性的、细胞外作用的DDR2变构抑制剂 (IC50:230 nM)。它通过受体的变构调节特异地抑制受体-配体相互作用。它通过靶向 DDR2 抑制肿瘤侵袭和迁移，基质的肿瘤支持作用，能够抑制肺中的转移性乳腺肿瘤细胞定植。
T41255	Specific PXR antagonist 70	Others	Others
	Specific PXR antagonist 70 是一种特异性孕烷 X 受体 (PXR) 拮抗剂，对人源 PXR 的 IC50 为 540 nM，Ki 为 390 nM，可增强癌细胞的化学敏感性。
TQ0219	MK-8033	c-Met/HGFR	Tyrosine Kinase/Adaptors
	MK-8033 是一种新型ATP 竞争性c-Met/Ron 双重抑制剂，对野生型c-Met 的IC50=1 nM，对c-Met N1100Y 的IC50=2.0 nM。
T21806	HNHA	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	HNHA 是组蛋白去乙酰化酶抑制剂。它通过 p21诱导将细胞周期阻滞在 G1/S 期，抑制肿瘤生长及肿瘤新生血管形成。HNHA 可能是一种有效的抗乳腺癌药物。
T9122	XL177A	DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	XL177A 是一种选择性不可逆的 USP7 抑制剂，IC50为 0.34 nM。它通过 p53 依赖性机制引发癌杀伤细胞作用。
T9582	CLEFMA	NF-κB	NF-κB
	CLEFMA 是一种姜黄素，抑制肿瘤生长与 NF-κB 调节的抗炎和抗转移作用有关，具有抗肿瘤活性。
T16522	Phenoxodiol 脱氢雌马酚,Dehydroequol,Idronoxil,Haginin E	Apoptosis; IAP; Caspase; Topoisomerase; p53	Apoptosis; DNA Damage/DNA Repair; Proteases/Proteasome
	Phenoxodiol (Idronoxil) 是合成genestein 的类似物，激活线粒体caspase 系统，抑制XIAP，使癌细胞对fas 介导的凋亡敏感。它在细胞周期的G1/S 期诱导细胞周期阻滞，通过独立于p53的方式上调p21WAF1。它通过稳定可分裂复合物抑制DNA 拓扑异构酶II，从而阻止DNA 复制。
T9407	Rasarfin	Others; Ras	GPCR/G Protein; MAPK; Others
	Rasarfin 是Ras 和ARF6双抑制剂。
T15461	Halopemide	Others; Phospholipase; Dopamine Receptor	GPCR/G Protein; Metabolism; Neuroscience; Others
	Halopemide 是一种有效的 PLD 抑制剂（对人 PLD1 和 PLD2 的 IC50 = 220 和 310 nM）。 Halopemid 是多巴胺受体的拮抗剂。Halopemid 可用于精神药物研究。
T22234	Alloxazine	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Alloxazine 是一种 A2 受体拮抗剂，其对 A2B 受体的选择性比对 A2A 受体的选择性高约 10 倍。
T0380	Bicalutamide 比卡鲁胺,ICI-176334	Androgen Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Bicalutamide (ICI-176334) 是一种具有口服活性的非甾体雄激素受体拮抗剂，可研究前列腺癌。
TP2333	cyclo(L-Pro-L-Tyr)	Others	Others
	cyclo(L-Pro-L-Tyr) 是真菌和细菌的次生代谢产物。
T2747	Endothall	Others	Others
	Endothall 是一种有效的蛋白磷酸酶 2A (PP2A) 抑制剂，对 PP2A 和 PP1 具有抑制作用， IC50 分别为 90 nM 和 5 µM。Endothall 具有抗癌活性，可用于癌症化疗，可用作除草剂。
T15598	Isosulfan blue	Others	Others
	Isosulfan blue 是用于淋巴管造影中淋巴管识别的蓝色染料，可用于乳腺癌前哨淋巴结活检，但其在乳腺癌手术中有发生过敏反应的可能性。
T38699	Piperafizine A
	Piperafizine A 是从 Streptoverticillium aspergilloides 中分离得到的，可增强 vincristine 的抗肿瘤效力。
T31011	Coralyne chloride	Topoisomerase	DNA Damage/DNA Repair
	Coralyne chloride 是一种具有强抗癌活性的原小檗碱。它可用于制备 Coralyne 衍生物，是一种基于荧光 DNA 的分子整流剂，通过位点特异性插入构建成 DNA 双链体。它可作为一种拓扑异构酶 I 毒性分子，诱导拓扑异构酶 I 介导 DNA 裂解。
T7698	BS194 (2S,3S)-3-[[3-(异丙基)-7-[(苯基甲基)氨基]吡唑并[1,5-A]嘧啶-5-基]氨基]-1,2,4-丁三醇	CDK	Cell Cycle/Checkpoint
	BS194 是一种有效的细胞周期蛋白依赖性蛋白激酶 (CDK) 抑制剂。
T8710	MSAB	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	MSAB 是一种Wnt/β-catenin 信号传导的选择性抑制剂。它能够与 β-catenin 结合，诱导其降解，并能够下调 Wnt/β-catenin 靶基因。它对 Wnt 依赖性癌细胞表现出有效的抗肿瘤特性。
T26357	Pitstop 2	Apoptosis	Apoptosis
	Pitstop2 是一种选择性的两性蛋白结合的网格蛋白末端结构域抑制剂，IC50 值为 12 μM。 Pitstop2 严重干扰受体介导的内吞作用、HIV 进入和突触小泡循环。
T9732	VY-3-135	Fatty Acid Synthase	Metabolism
	VY-3-135 是口服有效的乙酰辅酶 A 合成酶 2 (ACSS2)选择性抑制剂，IC50为 44 nM，对重组人 ACSS1 或 ACSS3 没有抑制活性。它有效抑制 ACSS2 依赖性脂肪酸代谢，但对肿瘤中的基因表达没有影响。
T6275	Obatoclax Mesylate Obatoclax,GX15-070,奥巴克拉甲磺酸盐	BCL; Parasite; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Obatoclax Mesylate (GX15-070) 是泛 BCL-2家族蛋白抑制剂，对 BCL-2 的 Ki 值为 220 nM。它是 BH3 模拟物，具有抗癌和广谱抗寄生虫活性。它诱导自噬依赖性细胞死亡，并靶向细胞周期蛋白 D1 进行蛋白酶体降解。
T9531	MRT-14	Smo	Stem Cells
	MRT-14 是有效的 Smo 拮抗剂。Smo 是参与 Hedgehog 形态发生素信号转导的主要成分。MRT-14 在研究与异常 Hh 信号传导相关的多种癌症方面有价值。
T12150	N-Methylbenzamide	PDE	Metabolism
	N-Methylbenzamide 是磷酸二酯酶 10A 抑制剂，具有抗癌作用。
TQ0186	Ko 143	BCRP; ABC	Membrane transporter/Ion channel
	Ko 143 有效且选择性抑制 ATP 结合盒亚家族 G 成员 2 (ABCG2/BCRP)
T60051	VPC-18005	Others	Others
	VPC-18005 是一种荧光素酶抑制剂。 VPC-18005 抑制 ERG 诱导的转录并直接与 ERG-ETS 结构域相互作用，从而破坏 ERG 与 DNA 的结合。
T7690	2-hydroxy Flutamide	Androgen Receptor	Endocrinology/Hormones
	2-hydroxy Flutamide 是 Flutamide 的活性代谢物，是雄激素受体拮抗剂，其 IC50值为700 nM。它可用于研究前列腺癌。
T17638	Boc-11-aminoundecanoic acid	Others; PROTAC Linker	Others; PROTAC
	Boc-11-aminoundecanoic acid 是一种属于 Alkyl/ether 类的 PROTAC linker，可用于 MS432 的合成。
T9060	STM2457	Apoptosis; Others	Apoptosis; Others
	STM2457 是一种 RNA 甲基转移酶 METTL3 的抑制剂 (IC50=16.9 nM)，具有选择性和口服活性。STM2457 可用于急性髓系白血病 (AML) 的研究。
T60026	KIF18A-IN-2	Microtubule Associated	Cytoskeletal Signaling
	KIF18A-IN-2 是有丝分裂驱动蛋白 Kif18A 的抑制剂，IC50 为 28 nM，可用于染色体不稳定性相关漏洞的研究。
T9008	NPD8733	Others	Others
	NPD8733 是癌细胞增强的成纤维细胞迁移抑制剂。它是与多种细胞活动 (AAA+) 蛋白家族相关的 ATP 酶的成员，能够与含 valosin 的蛋白 (VCP)/p97特异性结合，对癌症疾病具有潜在的研究价值。
T11929	M2N12	Phosphatase	Metabolism
	M2N12 是一种高度选择性的细胞分裂周期蛋白磷酸酶 25C 抑制剂，IC50值为 0.09 μM。它还抑制 Cdc25A 和 Cdc25B 的活性，IC50值分别为 0.53 μM 和 1.39 μM。它具有抗肿瘤活性，可研究癌症。
T4410	LM10	Others	Others
	LM10 是有效的色氨酸 2,3-双加氧酶的抑制剂。色氨酸 2,3-双加氧酶是一种无关的肝酶，它可通过犬尿氨酸途径降解色氨酸。它对研究癌症疾病具有潜在的研究价值。
T9831	MKC-1 Ro-31-7453	Apoptosis; Akt; Microtubule Associated; mTOR	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	MKC-1 (Ro-31-7453) 是一种口服生物可利用的小分子双吲哚基马来酰亚胺细胞周期抑制剂，具有潜在的抗肿瘤活性。
T3581	KS176	Potassium Channel; BCRP	Membrane transporter/Ion channel
	KS176是选择性高活性乳腺癌耐药蛋白多药转运通道抑制剂，在Pheo A 和Hoechst 检测中，IC50值分别为0.59和1.39 μM。
T14765	BOS-172722	Kinesin	Cytoskeletal Signaling
	BOS-172722 是一种单极纺锤体 1 (MPS1) 检查点抑制剂，对MPS1 (1 mM ATP) 和P-MPS1 的IC50值分别为 11 nM 和 63 nM。它可研究多种乳腺癌。

化合物

Cancer-Targeting Compound 1

Cat.No: T13572

Target: Others

33-BCRP Inhibitor

Cat.No: T83892

Synonym: 33-Breast Cancer Resistance Protein Inhibitor

Cat.No: T22336

Target: Dehydrogenase

Cat.No: T9929

Target: VEGFR

Cat.No: T2455

Synonym: PFK15,PFK 015

Target: Glucokinase, Autophagy

Cat.No: T9552

Target: Epigenetic Reader Domain

Cat.No: T8432

Target: AMPK

Cat.No: T2325

Synonym: HKI-272,来那替尼

Target: EGFR, HER

Cat.No: T60028

Target: DNA/RNA Synthesis

Cat.No: T9963

Target: HDAC

Cat.No: T1394

Synonym: Brufen,(±)-Ibuprofe,布洛芬,Motrin,Advil

Target: COX

Ibuprofen Lysine

Cat.No: T6540

Synonym: 布洛芬赖氨酸盐,Neoprofen

Target: COX

Bavdegalutamide

Cat.No: T22263

Synonym: ARV-110

Target: Androgen Receptor

Cat.No: T6816

Target: PKM

Cat.No: T8973

Target: Others

Cat.No: T17258

Target: Discoidin Domain Receptor (DDR)

Specific PXR antagonist 70

Cat.No: T41255

Target: Others

Cat.No: TQ0219

Target: c-Met/HGFR

Cat.No: T21806

Target: HDAC

Cat.No: T9122

Target: DUB

Cat.No: T9582

Target: NF-κB

Cat.No: T16522

Synonym: 脱氢雌马酚,Dehydroequol,Idronoxil,Haginin E

Target: Apoptosis, IAP, Caspase, Topoisomerase, p53

Cat.No: T9407

Target: Others, Ras

Cat.No: T15461

Target: Others, Phospholipase, Dopamine Receptor

Cat.No: T22234

Target: Adenosine Receptor

Cat.No: T0380

Synonym: 比卡鲁胺,ICI-176334

Target: Androgen Receptor, Autophagy

cyclo(L-Pro-L-Tyr)

Cat.No: TP2333

Target: Others

Cat.No: T2747

Target: Others

Cat.No: T15598

Target: Others

Cat.No: T38699

Coralyne chloride

Cat.No: T31011

Target: Topoisomerase

Cat.No: T7698

Synonym: (2S,3S)-3-[[3-(异丙基)-7-[(苯基甲基)氨基]吡唑并[1,5-A]嘧啶-5-基]氨基]-1,2,4-丁三醇

Target: CDK

Cat.No: T8710

Target: Wnt/beta-catenin

Cat.No: T26357

Target: Apoptosis

Cat.No: T9732

Target: Fatty Acid Synthase

Obatoclax Mesylate

Cat.No: T6275

Synonym: Obatoclax,GX15-070,奥巴克拉甲磺酸盐

Target: BCL, Parasite, Autophagy

Cat.No: T9531

Target: Smo

N-Methylbenzamide

Cat.No: T12150

Target: PDE

Cat.No: TQ0186

Target: BCRP, ABC

Cat.No: T60051

Target: Others

2-hydroxy Flutamide

Cat.No: T7690

Target: Androgen Receptor

Boc-11-aminoundecanoic acid

Cat.No: T17638

Target: Others, PROTAC Linker

Cat.No: T9060

Target: Apoptosis, Others

Cat.No: T60026

Target: Microtubule Associated

Cat.No: T9008

Target: Others

Cat.No: T11929

Target: Phosphatase

Cat.No: T4410

Target: Others

Cat.No: T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

Cat.No: T3581

Target: Potassium Channel, BCRP

Cat.No: T14765

Target: Kinesin

Cat. No.	Product Name	Target	Signaling Pathways
TN7020	Astragenol	Others	Others
	Astragenol 是合成黄芪醇衍生物的中间体。它的衍生物具有抗炎作用，可用于前列腺癌的研究。
TN1046	Murrayone	Others	Others
	Murrayone 是一种提取自M. paniculata 中的含有香豆素的化合物。Murrayone 具有独特的药理特性，可用作防止癌症转移的化学预防剂。
T3755	Pinostilbene	Others	Others
	Pinostilbene 是一种 Pterostilbene 的主要代谢物，能够抑制结肠癌细胞。
T5S0777	Phellodendrine chloride	Others	Others
	Phellodendrine chloride 是一种Phellodendron amurense 中的生物碱。它通过巨胞饮抑制营养物质的吸收，进而抑制 KRAS 突变的胰腺癌细胞的增殖。
T8188	Podophyllotoxone	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Podophyllotoxone 是从八角莲根中分离得到的一种天然产物，能抑制微管蛋白聚合，具有抗癌活性。
T2S1040	Jolkinolide B	ERK; IL Receptor; BCL; p38 MAPK; TNF; NF-κB; Akt; Caspase; PI3K; JAK; JNK; STAT; mTOR	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Jolkinolide B 是一种从 Euphorbia fischeriana Steud 的根中分离出来的具有生物活性的二萜。 Jolkinolide B 诱导癌细胞凋亡。 Jolkinolide B 可用于预防和治疗骨溶解的研究。
T2S0501	Ilexgenin A	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Ilexgenin A 是一种五环三萜类化合物，提取自海南冬青，可用于研究炎症及癌症。
T4S1173	Agrimol B 仙鹤草酚B,仙鹤草酚 B	Sirtuin; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Agrimol B 是从仙鹤草中分离得到的一种多酚衍生物，可抑制脂肪形成，降低PPARγ的表达，诱导SIRT1易位和表达。
TN1465	Cannabigerol	NOS; 5-HT Receptor; ROS	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cannabigerol 是一种植物大麻素，是一种高亲和力 α2-肾上腺素能受体激动剂、中度亲和力 5-HT1A 受体拮抗剂和低亲和力 CB1/CB2受体拮抗剂。它可降低眼压，有潜力治疗青光眼。
T8724	6-Methoxydihydrosanguinarine	Others	Others
	6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱，它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。
T5043	Lentinan	Others	Others
	Lentinan 是一种 β-葡聚糖，从香菇中提取获得。它在日本已被批准用作胃癌的生物反应调节剂。
T3055	Liensinine Perchlorate	Apoptosis; Others	Apoptosis; Others
	Liensinine Perchlorate 是元莲的成分，可诱导结直肠癌细胞凋亡，具有抗高血压和抗癌活性。
TQ0089	Juglanin	Apoptosis; JNK; Autophagy	Apoptosis; Autophagy; MAPK
	Juglanin 是来自金鸡脚的一种黄酮类天然产物，是一种 JNK 的激活剂，能诱导人乳腺癌细胞的凋亡和自噬，具有炎症和抗肿瘤活性。
TN2054	Periplocymarin	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Periplocymarin 是一种强心苷，从 Periploca sepium 和 Periploca graeca 中分离得到，具有抗癌潜力。
T38815	Millepachine	Apoptosis	Apoptosis
	Millepachine 是分离自中草药Millettia pachycarpaBenth 的查尔酮，在体内外对多种人类癌细胞均显示出强大的抗增殖作用。
T0724	Formononetin Biochanin B,Flavosil,刺芒柄花素,Formononetol	Apoptosis; FGFR	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Formononetin (Flavosil) 是一种 FGFR2抑制剂，IC50约为4.31 μM。它是一种 O-甲基化的异黄酮，是来自黄芪根的植物雌激素，可有效抑制血管生成和肿瘤生长。
TN7041	(-)-Epipodophyllotoxin	Apoptosis	Apoptosis
	(-)-Epipodophyllotoxin 是一种从八角莲中分离的癌细胞抗增殖剂，在 HeLa 细胞和 MCF-7 细胞中的GI50值分别为 0.36 和 0.24 μM。它可在体外抑制有丝分裂纺锤体组装。
TN1722	Hamamelitannin	Antifection	Microbiology/Virology
	Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚，是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。
T19470	Nandrolone propionate	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Nandrolone propionate 是合成代谢类固醇，主要由雄激素和保氮剂组成，具有作用时间相对较长的特点。
T3S0872	Paederoside	Antiviral; HBV	Immunology/Inflammation; Microbiology/Virology
	Paederoside 是从Paederia pertomentosa 分离的一种单萜 S-甲基硫代碳酸酯。它抑制 Epstein-Barr 病毒的激活，有抗肿瘤促进作用。
T1181	Gefitinib ZD1839,吉非替尼	EGFR; Tyrosine Kinases; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Gefitinib (ZD1839) 是一种 EGFR 一代抑制具有口服活性，抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
TN2883	3',4'-Dimethoxyflavone	Others; PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
	3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准，类黄酮化合物具有多种药用活性。
T2988	(-)-Epigallocatechin Gallate Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG	Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	(-)-Epigallocatechin Gallate (EGCG) 是茶类黄酮，具有强大的抗氧化，抗炎和抗癌作用。它可抑制EGFR 信号传导，有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。
TN2097	Pomolic acid 坡模酸	Apoptosis; Caspase; HIV Protease; AMPK	Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长，诱导细胞凋亡，有用于前列腺癌的潜力。
T5755	Aloesin	Tyrosinase	Proteases/Proteasome
	Aloesin 是芦荟的活性成分之一，能够通过 MAPK 信号通路发挥抗癌作用，并具有抗炎、紫外线保护和抗菌作用。
T5S1099	Liensinine	Apoptosis; Mitophagy; Others; Autophagy	Apoptosis; Autophagy; Others
	Liensinine 是一种自噬/线粒体自噬抑制剂。Liensinine 是从芙蕖种子胚中提取的，一种主要的异喹啉生物碱，具抗心律不齐、抗高血压、抗肺纤维化、血管平滑肌松弛等广泛的生物活性。
TN1493	Chrysosplenol D 猫眼草酚D	IL Receptor; NF-κB; JNK	Immunology/Inflammation; MAPK; NF-κB
	Chrysosplenol D 属于甲氧基黄酮类化合物，可诱导 ERK1/2 介导的三阴性人乳腺癌细胞凋亡。它还显示出抗炎和中等抗锥虫活性。
TN2252	Syrosingopine	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Syrosingopine 是 MCT1和 MCT4双重抑制剂，对 MCT4 的效力高 60 倍，可防止乳酸和 H+ 流出。它是可口服抗高血压药物，联合二甲双胍具有研究癌症疾病的潜力。
TN2080	Pinoresinol 松脂酚，松脂素,(+)-Pinoresinol	Apoptosis; NF-κB; CDK; p53	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Pinoresinol ((+)-Pinoresinol) 是一种植物来源的木质素，具有抗炎、保肝和杀真菌活性。它导致 CDK 抑制剂 p21(WAF1/Cip1) 在 mRNA 和蛋白质水平上调，抑制 NF-kappaB 和激活蛋白 1 。
T3862	Irigenin	NF-κB; Integrin	Cytoskeletal Signaling; NF-κB
	Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点，介导其抗转移作用。可通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡，具有抗癌作用。
T4S1999	Valepotriate 戊曲酯/缬草素,Valtrate	Apoptosis; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Valepotriate (Valtrate) 是从蜘蛛香分离而来的一种天然产物，是一类新的细胞毒剂和抗肿瘤剂，对 HTC 肝癌细胞是非常有效的细胞毒剂。它可能对焦虑的精神症状具有潜在的抗焦虑作用。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
TN1839	Kumatakenin Jaranol,华良姜素，熊竹素,Kaempferol 3,7-O-dimethyl ether	Apoptosis; Anti-infection	Apoptosis; Microbiology/Virology
	Kumatakenin 是一种从丁香中分离得到的黄酮类天然产物，可诱导卵巢癌细胞凋亡。
T21165	Pellitorine AI3-19560,墙草碱,Pellitorin	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pellitorine (Pellitorin) 是提取自 Piper nigrum 的根的一种化合物。它对 HL60 和 MCT-7 细胞系表现出显著的细胞毒活性。它可用于癌症疾病的研究。
TN1153	Polyporenic acid C 猪苓酸C,聚孔酸C	Apoptosis; PARP; Caspase; PI3K	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Polyporenic acid C 是从茯苓中分离出的一种羊毛甾烷型三萜，可通过死亡受体介导的凋亡途径诱导细胞凋亡，有用于肺癌的研究潜力。
T4820	Maleimide 马来酰亚胺,2,5-Pyrroledione	Others	Others
	Maleimide (2,5-Pyrroledione) 可用于制备荧光探针，主要用于硫醇分析物的特异性检测。它也可用于制备用于癌症研究的抗体-药物偶联物 (ADC)。
T13229	Tunicamycin	Influenza Virus; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Tunicamycin 是一种抗生素的混合物，通过阻断 GlcNAc 磷酸转移酶 (GPT)，抑制 N-连接糖基化。Tunicamycin 具有抗肿瘤活性，还具有抗细菌、抗真菌和抗病毒活性。
TN6720	Acetylalkannin Acetyl alkannin,Alkannin acetate	Antibacterial	Microbiology/Virology
	Acetylalkannin (Alkannin acetate) 是一种从 Arnebia euchroma 中分离出来的异己烯基萘色素，具有抗菌和细胞毒性作用。
TN2190	Scoulerine	Apoptosis; Beta-Secretase; BACE; Parasite	Apoptosis; Microbiology/Virology; Neuroscience
	Scoulerine 是抗有丝分裂化合物。它抑制细胞增殖，阻止细胞周期，并诱导癌细胞凋亡。它也是BACE1(淀粉样前体蛋白裂解酶 1) 的抑制剂。
TN3967	Epieriocalyxin A	ERK; BCL; ROS; Caspase; DNA/RNA Synthesis; JNK	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Proteases/Proteasome
	Epieriocalyxin A 可以抑制 Caco-2 结肠癌细胞的生长。它可能是未来结肠癌治疗的潜在药物。
TN2269	Tetramethylcurcumin	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	Tetramethylcurcumin 是一种新型姜黄素类似物，是一种有效的 STAT3 磷酸化、DNA 结合活性和体外反式激活抑制剂。它具有抗炎和抗癌作用。
TN2082	Pinostrobin	Beta Amyloid; IL Receptor; Serine/threonin kinase; TNF	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
	Pinostrobin 是一种 PCSK9抑制剂，可抑制 PCSK9 的催化活性。它是能够在多种植物中发现的黄酮类化合物，并具有抗氧化，抗炎，抗癌和神经保护作用。它是有前景的胆固醇调节和脂质管理剂。
T11366	Garcinol	Apoptosis; Endogenous Metabolite; Histone Acetyltransferase; AChR; AChE	Apoptosis; Chromatin/Epigenetic; Metabolism; Neuroscience
	Garcinol 是一种从印度藤黄提取的聚异戊二烯基二苯甲酮，对乙酰胆碱酯酶和丁酰胆碱酯酶具有抗胆碱酯酶的特性，IC50分别为 0.66 µM 和 7.39 µM。它还抑制组蛋白乙酰转移酶和 p300/CPB 相关因子，具有抗炎和抗癌活性。
T5808	(-)-Oxypeucedanin hydrate 水合氧化前胡素,OXYPEUCEDANIN HYDRATE	Others	Others
	(-)-Oxypeucedanin hydrate 是一种呋喃香豆素衍生物，分离自Ducrosia anethifolia 中。
T5739	Paederosidic acid 鸡屎藤苷酸,异戊二酸紫草酸	Apoptosis; BCL	Apoptosis
	Paederosidic acid 是从鸡矢藤分离出的一种天然产物，通过诱导线粒体介导的凋亡抑制肺癌细胞，具有显着的抗肿瘤、抗惊厥和镇静作用。
T1590	Letrozole CGS 20267,来曲唑	Aromatase; Autophagy	Autophagy; Endocrinology/Hormones
	Letrozole (CGS 20267) 是一种可口服的，选择性可逆的非甾体类芳香化酶抑制剂，IC50值为 11.5 nM。它选择性抑制雌激素的生物合成，可研究乳腺癌。
TN1788	Isookanin	Amylase	Metabolism
	Isookanin 在多种疾病领域有研究价值，包括肿瘤，皮疹，蛇和昆虫叮咬，糖尿病，腹泻。它可作为抗病毒剂对抗 HSV 和水痘带状疱疹病毒。它也具有抗氧化特性。
T5061	Lumichrome 7,8-Dimethylalloxazine,光色素	Others	Others
	Lumichrome (7,8-Dimethylalloxazine) 是人类体内的内源性化合物，由核黄素光降解产生。它利用 p53 依赖机制抑制人肺癌细胞生长并诱导凋亡。
T2217	Cephalomannine Baccatin III,三尖杉宁碱	Microtubule Associated	Cytoskeletal Signaling
	Cephalomannine (Baccatin III) 是一种从云南红豆杉中提取的紫杉醇衍生物，具有抗肿瘤活性，可用于癌症研究。
T6795	Carbidopa 卡比多巴,(S)-(-)-Carbidopa,Lodosyn	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa (Lodosyn) 是一种选择性芳香烃受体(AhR)调节剂，是外周型脱羧酶抑制剂，抑制胰腺癌细胞和肿瘤生长，可用于帕金森病的研究。
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天然产物

Cat.No: TN7020

Target: Others

Cat.No: TN1046

Target: Others

Cat.No: T3755

Target: Others

Phellodendrine chloride

Cat.No: T5S0777

Target: Others

Podophyllotoxone

Cat.No: T8188

Target: Others, Microtubule Associated

Cat.No: T2S1040

Target: ERK, IL Receptor, BCL, p38 MAPK, TNF, NF-κB, Akt, Caspase, PI3K, JAK, JNK, STAT, mTOR

Cat.No: T2S0501

Target: IL Receptor, TNF

Cat.No: T4S1173

Synonym: 仙鹤草酚B,仙鹤草酚 B

Target: Sirtuin, PPAR

Cat.No: TN1465

Target: NOS, 5-HT Receptor, ROS

6-Methoxydihydrosanguinarine

Cat.No: T8724

Target: Others

Cat.No: T5043

Target: Others

Liensinine Perchlorate

Cat.No: T3055

Target: Apoptosis, Others

Cat.No: TQ0089

Target: Apoptosis, JNK, Autophagy

Cat.No: TN2054

Target: Calcium Channel

Cat.No: T38815

Target: Apoptosis

Cat.No: T0724

Synonym: Biochanin B,Flavosil,刺芒柄花素,Formononetol

Target: Apoptosis, FGFR

(-)-Epipodophyllotoxin

Cat.No: TN7041

Target: Apoptosis

Cat.No: TN1722

Target: Antifection

Nandrolone propionate

Cat.No: T19470

Target: Others, Androgen Receptor

Cat.No: T3S0872

Target: Antiviral, HBV

Cat.No: T1181

Synonym: ZD1839,吉非替尼

Target: EGFR, Tyrosine Kinases, Autophagy

3',4'-Dimethoxyflavone

Cat.No: TN2883

Target: Others, PARP

(-)-Epigallocatechin Gallate

Cat.No: T2988

Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Cat.No: TN2097

Synonym: 坡模酸

Target: Apoptosis, Caspase, HIV Protease, AMPK

Cat.No: T5755

Target: Tyrosinase

Cat.No: T5S1099

Target: Apoptosis, Mitophagy, Others, Autophagy

Chrysosplenol D

Cat.No: TN1493

Synonym: 猫眼草酚D

Target: IL Receptor, NF-κB, JNK

Cat.No: TN2252

Target: Dopamine Receptor

Cat.No: TN2080

Synonym: 松脂酚，松脂素,(+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Cat.No: T3862

Target: NF-κB, Integrin

Cat.No: T4S1999

Synonym: 戊曲酯/缬草素,Valtrate

Target: Apoptosis, HIV Protease

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: TN1839

Synonym: Jaranol,华良姜素，熊竹素,Kaempferol 3,7-O-dimethyl ether

Target: Apoptosis, Anti-infection

Cat.No: T21165

Synonym: AI3-19560,墙草碱,Pellitorin

Target: TRP/TRPV Channel

Polyporenic acid C

Cat.No: TN1153

Synonym: 猪苓酸C,聚孔酸C

Target: Apoptosis, PARP, Caspase, PI3K

Cat.No: T4820

Synonym: 马来酰亚胺,2,5-Pyrroledione

Target: Others

Cat.No: T13229

Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal

Cat.No: TN6720

Synonym: Acetyl alkannin,Alkannin acetate

Target: Antibacterial

Cat.No: TN2190

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Epieriocalyxin A

Cat.No: TN3967

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Tetramethylcurcumin

Cat.No: TN2269

Target: Apoptosis, STAT

Cat.No: TN2082

Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF

Cat.No: T11366

Target: Apoptosis, Endogenous Metabolite, Histone Acetyltransferase, AChR, AChE

(-)-Oxypeucedanin hydrate

Cat.No: T5808

Synonym: 水合氧化前胡素,OXYPEUCEDANIN HYDRATE

Target: Others

Paederosidic acid

Cat.No: T5739

Synonym: 鸡屎藤苷酸,异戊二酸紫草酸

Target: Apoptosis, BCL

Cat.No: T1590

Synonym: CGS 20267,来曲唑

Target: Aromatase, Autophagy

Cat.No: TN1788

Target: Amylase

Cat.No: T5061

Synonym: 7,8-Dimethylalloxazine,光色素

Target: Others

Cat.No: T2217

Synonym: Baccatin III,三尖杉宁碱

Target: Microtubule Associated

Cat.No: T6795

Synonym: 卡比多巴,(S)-(-)-Carbidopa,Lodosyn

Target: Decarboxylase, Aryl Hydrocarbon Receptor

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01594	CT83 Protein-VLP, Human, Recombinant (His) CXorf61,KK-LC-1,Cancer/testis antigen 83,Kita-kyush...	Human	HEK293
	CT83 Protein-VLP, Human, Recombinant (His) is expressed in HEK293.
TMPH-01593	CT83 Protein, Human, Recombinant (E. coli, His) CXorf61,Kita-kyushu lung cancer antigen 1,KKLC1,KK-...	Human	E. coli
	CT83 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-01033	CTAG1A Protein, Human, Recombinant (His) CT6.1,LAGE2,CTAG,CTAG1,L antigen family member 2,LAGE2A,ESO1...	Human	E. coli

TMPH-01034	CTAG1A Protein, Human, Recombinant (hFc & Myc) CTAG1,ESO1,LAGE-2,CT6.1,LAGE2,L antigen family member 2,CTAG...	Human	HEK293

TMPH-00884	ACTL8 Protein, Human, Recombinant (His & Myc) Cancer/testis antigen 57,CT57,Actin-like protein 8	Human	Baculovirus

TMPH-00885	ACTL8 Protein, Human, Recombinant (E. coli, His & Myc) Actin-like protein 8,CT57,Cancer/testis antigen 57	Human	E. coli

TMPH-01901	DDX53 Protein, Human, Recombinant (His & Myc) DEAD box protein CAGE,DEAD box protein 53,CAGE,CT26,Probable...	Human	E. coli
	DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01357	ALDOA Protein, Human, Recombinant (His) Muscle-type aldolase,Lung cancer antigen NY-LU-1,Fr...	Human	E. coli
	Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.
TMPJ-01061	Nucleobindin-2 Protein, Human, Recombinant NUCB2,NEFA,Gastric cancer antigen Zg4,Nesfatin-1,Pr...	Human	E. coli
	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may ...
TMPH-01091	CHD1L Protein, Human, Recombinant (His & SUMO) Amplified in liver cancer protein 1,CHD1L,ALC1,Chro...	Human	E. coli
	DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
TMPH-03747	CCDC112 Protein, Human, Recombinant (His & Myc) Mutated in bladder cancer protein 1,Coiled-coil dom...	Human	E. coli

TMPJ-01032	SPINK7 Protein, Human, Recombinant (His) ECG2,SPINK7,Serine protease inhibitor Kazal-type 7,ECRG-2,Es...	Human	Human Cells
	Serine protease inhibitor Kazal-type 7(SPINK7) is a secreted protein, that in humans is encoded by the SPINK7 gene. SPINK7 contains 1 Kazal-like domain. SPINK7 is probably serine protease inhibitor. Recombinant human SPINK7 is a single, non-glycosylated polypeptide chain containing 74 amino acids and fused to His-tag at c-terminus.
TMPJ-00706	SNCG Protein, Human, Recombinant PRSN,Gamma-Synuclein,SNCG,BCSG1,Breast Cancer-Speci...	Human	E. coli
	Gamma-Synuclein (SNCG) is a member of the Synuclein protein family. Gamma-Synuclein is mostly expressed in the peripheral nervous system and retina. Gamma-Synuclein plays a role in neurofilament network integrity and may be involved in modulating axonal architecture during development and in the adult. In addition, it may also function in modulating the keratin network in skin. SNCG expression in breast tumors has been as a marker for tumor progression. SNCG is also believed to be involved in th...
TMPJ-01432	CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated mucin 16, cell surface associated,CA-125,CA125 ovarian c...	Human	Human Cells
	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by tumor cells including ovarian and mesothelial cancers. The transmembrane form can adhere to mesothelin in the peritoneum, facilitating metastasis of ovarian cancer to the peritoneal cavity. MUC16 also binds galectin-1 on immune cells and enhances its expression on tumor cells. MUC...
TMPJ-00050	AG-3 Protein, Human, Recombinant (His) BCMP11,hAG-3,AG-3,AG3,Anterior Gradient Protein 3 Homolog,Br...	Human	Human Cells
	Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
TMPJ-00281	CADM1 Protein, Mouse, Recombinant (hFc) IgSF4,NECL-2,Nectin-like protein 2,Immunoglobulin superfamil...	Mouse	Human Cells
	Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in...
TMPH-03526	Cap8A Protein, S. aureus, Recombinant (His) MAGEB2,MAGE XP-2 antigen,DAM6,MAGE-B2 antigen,Melanoma-assoc...	Staphylococcus aureus	in vitro E. coli expression system
	May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated Polymorphic epithelial mucin,KL-6,Cancer antigen 15...	Human	Human Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His) VEGFR-3,PCL,FLT41,VEGF Receptor 3,VEGFR3,FLT-4,fms related t...	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEGFR3,AI323...	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-05030	PCDH7 Protein, Human, Recombinant (His) BHPCDH	Human	Baculovirus-Insect Cells
	PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC).
TMPY-01356	S100A8 Protein, Human, Recombinant (His) 60B8AG,MRP-8,MA387,NIF,L1Ag,S100 calcium binding protein A8,...	Human	Baculovirus-Insect Cells
	S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells...
TMPY-03016	CD24 Protein, Mouse, Recombinant (hFc) Ly-52,CD24 molecule,Cd24a,CD24	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-01431	L1CAM Protein, Human, Recombinant (His) N-CAM-L1,MASA,HSAS,L1 cell adhesion molecule,MIC5,N-CAML1,CD...	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif ...
TMPY-03156	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) vascular endothelial growth factor C	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGF...
TMPY-00365	GALNT7 Protein, Human, Recombinant (His) GalNAcT7,polypeptide N-acetylgalactosaminyltransferase 7,GAL...	Human	HEK293
	GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. GALNT7 acts as a glycosyltransferase in protein O-glycosylation, involving in the occurrence and development of CRC. GALNT7 silencing significantly attenuated the proliferation, clonogenicity and migration of LSCC cells a...
TMPY-01730	CD24 Protein, Human, Recombinant (hFc) CD24A,FLJ43543,CD24 molecule,FLJ22950,MGC75043	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His) insulin-like growth factor binding protein 3,IBP3,BP-53,IGFB...	Human	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory, apoptosis-inducing molecule, capable of acting via IGF-dependent and IGF-independent mechanisms. It appears to function both by cell cycle blockade and the induction of apoptosis. IGFBP3 can be transported to the nucleus by an importin beta mediated mechanism, where it has been...
TMPY-01477	MMP-2 Protein, Human, Recombinant TBE-1,MMP-II,matrix metallopeptidase 2,MONA,CLG4,CLG4A,MMP-2	Human	HEK293
	Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is dependent on extracellular matrix metalloproteinase inducer (EMMPRIN), Her2/neu, growth factors, cytokines, and hormones. Pro-MMP-2 activation needs MT1-MMP and TIMP-2 contribution. MMP-2 is changed in distribution and increased in amount in the ventral cochlear nucleus after unila...
TMPY-00570	Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placental,IAP,AL...	Human	Yeast
	Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
TMPY-03564	TSPAN8 Protein, Human, Recombinant (His) CO-029,tetraspanin 8,TM4SF3	Human	HEK293
	Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a negative regulator of Tspan8 expression. p53 as a regulator of melanoma invasion and the concept that reactivating p53 could provide a strategy for modulating not only proliferative but also invasive capacity in melanoma treatment. Tetraspanin 8 (TSPAN8) is a tumor-associated antigen...
TMPY-01007	VEGFC Protein, Human, Recombinant (His) 血管内皮生长因子,LMPH1D,VEGF-C,Flt4-L,vascular endothelial growth fa...	Human	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. VEGF-C protein is over-expressed in various human cancers including breast cancer and prostate cancer. VEGF-C/VEGF...
TMPY-02412	ENO1 Protein, Human, Recombinant (His) PPH,NNE,enolase 1, (alpha),ENO1L1,HEL-S-17,MPB1,enolase 1, (...	Human	E. coli
	The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ...
TMPY-01121	DKK3 Protein, Mouse, Recombinant (His) dickkopf WNT signaling pathway inhibitor 3,C87148,AW061014	Mouse	HEK293
	DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its...
TMPY-02778	ENPP2 Protein, Human, Recombinant (His) ATX,ectonucleotide pyrophosphatase/phosphodiesterase 2,AUTOT...	Human	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The Autotaxin protein is important for generating the lipid signaling molecule lysophosphatidic acid (LPA), which is a potent mitogen, which facilitates cell proliferation and migration, neurite retr...
TMPY-03762	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) cadherin 1, type 1, E-cadherin (epithelial),Arc-1,E-Cadherin...	Human	HEK293
	Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lo...
TMPY-01744	ACVR2A Protein, Human, Recombinant (His) activin A receptor, type IIA,ACVR2,ACTRII	Human	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately 98% identity) to the rat, mouse, and human ACVR2A proteins. Inactivation of ACVR2A is a common event in prostate cancer cells suggesting it may play an important role in the development of prostate cancer. The ACVR2A gene is a putative tumor suppressor gene that is frequently mu...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc) leucine rich repeat containing 15,LIB	Human	HEK293
	LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmembrane protein demonstrated to play important roles in cancer. LRRC15 is highly expressed in multiple solid tumor indications with limited normal tissue expression. It was expressed on stromal fibroblasts in many solid tumors (e.g., breast, head, and neck, lung, pancreatic) as well...
TMPY-00566	CCL18 Protein, Human, Recombinant (His) PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...	Human	Yeast
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a...
TMPY-00476	ITGB1 Protein, Human, Recombinant (His) VLAB,integrin, beta 1 (fibronectin receptor, beta polypeptid...	Human	HEK293
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-01447	ACVR2A Protein, Mouse, Recombinant (His) ActrIIa,activin A receptor, type IIA,Acvr2,TactrII	Mouse	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately 98% identity) to the rat, mouse, and human ACVR2A proteins. Inactivation of ACVR2A is a common event in prostate cancer cells suggesting it may play an important role in the development of prostate cancer. The ACVR2A gene is a putative tumor suppressor gene that is frequently mu...
TMPY-00463	ENPP2 Protein, Cynomolgus, Recombinant (His) ENPP2,ectonucleotide pyrophosphatase/phosphodiesterase 2,Aut...	Cynomolgus	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The Autotaxin protein is important for generating the lipid signaling molecule lysophosphatidic acid (LPA), which is a potent mitogen, which facilitates cell proliferation and migration, neurite retr...
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMOR1,DTD,DH...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His) GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF15,PTGFBPTGF-beta,NAG-1,P...	Rat	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
TMPY-04153	RNF43 Protein, Human, Recombinant (His) ring finger protein 43,URCC,RNF43,RNF124	Human	HEK293
	RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expressed oncogenes in malignant colorectal tumors. RNF43 is a tumour suppressor gene that suppresses the Wnt-beta-catenin signalling pathway.
TMPY-02938	REG4 Protein, Rat, Recombinant (His) regenerating islet-derived family, member 4	Rat	HEK293
	Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel dise...
TMPH-00005	YAP1 Protein, Human, Recombinant (Isoform 9, His) YAP1-2delta	Human	Yeast

TMPY-05337	CXCL16 Protein, Human, Recombinant (His) chemokine (C-X-C motif) ligand 16,CXCLG16,SR-PSOX,SRPSOX	Human	HEK293
	C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmembrane and soluble forms. The transmembrane form acts as a scavenger receptor for oxidised LDL whereas the soluble form acts a chemoattractant for mainly CD8+ T cells. CXCL16 is a protein which shares pattern recognition receptor functions, relevant for adhesion and phagocytosis of...
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His) A630052E07Rik,OSF-2,Osf2,PLF,AI747096,peri,PN,periostin, ost...	Mouse	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced ...
TMPY-01884	MMP-8 Protein, Human, Recombinant CLG1,HNC,PMNL-CL,matrix metallopeptidase 8,MMP-8	Human	HEK293
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a memb...
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重组蛋白

CT83 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01594

Species: Human

Expression System: HEK293

CT83 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01593

Species: Human

Expression System: E. coli

CTAG1A Protein, Human, Recombinant (His)

Cat.No: TMPH-01033

Species: Human

Expression System: E. coli

CTAG1A Protein, Human, Recombinant (hFc & Myc)

Cat.No: TMPH-01034

Species: Human

Expression System: HEK293

ACTL8 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00884

Species: Human

Expression System: Baculovirus

ACTL8 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-00885

Species: Human

Expression System: E. coli

DDX53 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01901

Species: Human

Expression System: E. coli

ALDOA Protein, Human, Recombinant (His)

Cat.No: TMPH-01357

Species: Human

Expression System: E. coli

Nucleobindin-2 Protein, Human, Recombinant

Cat.No: TMPJ-01061

Species: Human

Expression System: E. coli

CHD1L Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01091

Species: Human

Expression System: E. coli

CCDC112 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-03747

Species: Human

Expression System: E. coli

SPINK7 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01032

Species: Human

Expression System: Human Cells

SNCG Protein, Human, Recombinant

Cat.No: TMPJ-00706

Species: Human

Expression System: E. coli

CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

Cat.No: TMPJ-01432

Species: Human

Expression System: Human Cells

AG-3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00050

Species: Human

Expression System: Human Cells

CADM1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00281

Species: Mouse

Expression System: Human Cells

Cap8A Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03526

Species: Staphylococcus aureus

Expression System: in vitro E. coli expression system

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

Cat.No: TMPJ-00155

Species: Human

Expression System: Human Cells

VEGFR3/FLT4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00949

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01936

Species: Mouse

Expression System: HEK293

PCDH7 Protein, Human, Recombinant (His)

Cat.No: TMPY-05030

Species: Human

Expression System: Baculovirus-Insect Cells

S100A8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01356

Species: Human

Expression System: Baculovirus-Insect Cells

CD24 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03016

Species: Mouse

Expression System: HEK293

L1CAM Protein, Human, Recombinant (His)

Cat.No: TMPY-01431

Species: Human

Expression System: HEK293

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)

Cat.No: TMPY-03156

Species: Mouse,Rat

Expression System: HEK293

GALNT7 Protein, Human, Recombinant (His)

Cat.No: TMPY-00365

Species: Human

Expression System: HEK293

CD24 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01730

Species: Human

Expression System: HEK293

IGFBP-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-00835

Species: Human

Expression System: HEK293

MMP-2 Protein, Human, Recombinant

Cat.No: TMPY-01477

Species: Human

Expression System: HEK293

Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

Cat.No: TMPY-00570

Species: Human

Expression System: Yeast

TSPAN8 Protein, Human, Recombinant (His)

Cat.No: TMPY-03564

Species: Human

Expression System: HEK293

VEGFC Protein, Human, Recombinant (His)

Cat.No: TMPY-01007

Species: Human

Expression System: HEK293

ENO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02412

Species: Human

Expression System: E. coli

DKK3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01121

Species: Mouse

Expression System: HEK293

ENPP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02778

Species: Human

Expression System: HEK293

E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03762

Species: Human

Expression System: HEK293

ACVR2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01744

Species: Human

Expression System: HEK293

LRRC15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04333

Species: Human

Expression System: HEK293

CCL18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00566

Species: Human

Expression System: Yeast

ITGB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00476

Species: Human

Expression System: HEK293

ACVR2A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01447

Species: Mouse

Expression System: HEK293

ENPP2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-00463

Species: Cynomolgus

Expression System: HEK293

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

GDF-15 Protein, Rat, Recombinant (His)

Cat.No: TMPK-01243

Species: Rat

Expression System: E. coli

RNF43 Protein, Human, Recombinant (His)

Cat.No: TMPY-04153

Species: Human

Expression System: HEK293

REG4 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02938

Species: Rat

Expression System: HEK293

YAP1 Protein, Human, Recombinant (Isoform 9, His)

Cat.No: TMPH-00005

Species: Human

Expression System: Yeast

CXCL16 Protein, Human, Recombinant (His)

Cat.No: TMPY-05337

Species: Human

Expression System: HEK293

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01613

Species: Mouse

Expression System: HEK293

MMP-8 Protein, Human, Recombinant

Cat.No: TMPY-01884

Species: Human

Expression System: HEK293

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