Name: Sacituzumab govitecan
Brand: TargetMol
SKU: T77824
Price: 3650 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 3,650

现货

5 mg

¥ 7,860

现货

10 mg

¥ 10,600

现货

25 mg

¥ 15,700

现货

生物活性

产品描述	Sacituzumab govitecan (IMMU-132) is a humanized ADC compound targeting Trop-2 with anticancer activity for the study of refractory, locally advanced or metastatic breast cancer and uroepithelial cancer.
体内活性	Sacituzumab govitecan 以17.5 mg/kg的剂量，每周两次，连续四周给药，在携带人类胃癌异种移植肿瘤的小鼠中显示了显著的抗肿瘤效果。[1]
表达系统	CHO
别名	戈维替康-沙西妥珠单抗, IMMU-132
反应种属	Human
验证活性	Immobilized Human TROP2 Protein (ECD, His) at 2 μg/mL (30 μL/well) can bind Sacituzumab govitecan. The EC50 is 0.005813 μg/mL.
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1 EU/mg

抗体信息

同型	Human IgG1-REM kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联

SN38

抗原信息

Uniprot ID	P09758
靶点	TROP-2

化学信息

分子量	148.74 kDa
CAS No.	1491917-83-9

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: 20.00 mg/mL, Sonication is recommended.

Sacituzumab govitecan