p 3

Ebopiprant, also known as OBE-022, is an Oral and Selective Prostaglandin F 2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor. OBE022 exhibits potent tocolytic effects on human tissues ex vivo and animal models in vivo without causing the adverse fetal side effects seen with indomethacin.

JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导，也可阻碍内皮单层细胞迁移和血管生成，影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is a second messenger that promotes the release of calcium ions from the endoplasmic reticulum.

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references and .

N-Demethylansamitocin P-3, a derivative of Ansamitocin, an antitumor ansamycin antibiotic, can be synthesized through the action of Streptomyces minutiscleroticus IFO 13361.

Anti-CEACAM7 Antibody (P3-7B) 为小鼠IgG1, κ 类型嵌合抗体，专门针对CEACAM7(人源)。该抗体的同型对照是 MouseIgG1kappa, Isotype Control。

18:0-20:4 PI(3,4,5)P3 (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium)) 一种在生化反应中使用的试剂。

18:1 PI(3,4,5)P3 一种在生化反应中使用的试剂。

Ganglioside GM1-bindingpeptidesp3 为一种人工合成多肽，具备与GM1神经节苷脂的五糖部分进行特异性结合的能力。该多肽的动态转变对于理解GM1在多种受体功能中的作用至关重要，特别是在霍乱毒素感染的常见途径上。此外，Ganglioside GM1-bindingpeptidesp3 还常被应用于研究GM1与其配体之间的相互作用。

PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (DOPI-3,4,5-P3) sodium 是一种磷脂酰肌醇的类似物。

18:0-20:4 PI(3,4,5)P3 (sodium) 是磷脂酰肌醇的类似物，其与 PtdIns-(3,4,5)-P3 结合对细胞骨架重排和膜运输起关键作用。PtdIns-(3,4,5)-P3 不易被 PI 特异性 PLC 切割。

PtdIns-(3,4,5)-P3-(1-stearoyl, 2-arachidonoyl) sodium 是磷脂酰肌醇-3,4,5-三磷酸 (PIP3) 的一种特定分子形式。PIP3 在酪氨酸激酶通路中作为核心脂质信使，通过招募效应蛋白来调控细胞增殖、生存和代谢，其异常表达与癌症的发生有关。PtdIns-(3,4,5)-P3-(1-stearoyl, 2-arachidonoyl) sodium 可用于研究脂质信号传导。

Ansamitocin P 3' (Maytansinol butyrate) 是一种具有抗肿瘤活性的抗体-药物偶联细胞毒素。

Midecamycin (Medecamycin A1) 是乙酰氧基取代的大环内酯类抗生素，对革兰氏阳性和阴性菌有效。

CBP/p300-IN-3 (P300/CBP-IN-3) 是一种组蛋白乙酰转移酶抑制剂。

p-3-Methylamino propyl phenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125046。

Ansamitocin p-3 (Maytansinol isobutyrate) 是一种微管抑制剂，对微管蛋白聚合的 IC50 为 3.4 μM。

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.

Ginsenoside Ro (Chikusetsusaponin V) 能降低 TXA2产量，较弱降低 COX-1 和 TXAS 活性，具有 Ca2+拮抗剂的抗血小板作用，IC50为 155 μM。

Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种高选择性、强效的 P - 糖蛋白（P-gp， ABCB1）竞争性抑制剂，Ki 值为 59 nM。Zosuquidar trihydrochloride 具有抗肿瘤活性，可用于白血病等肿瘤研究。

D-myo-Inositol-1,2,6-triphosphate (sodium) 是肌醇磷酸第二信使家族的成员之一，在细胞信号传递中至关重要。它与内质网受体结合后，会开放钙通道，从而增加细胞内钙离子浓度。

D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) 是由磷脂酰肌醇-4,5-二磷酸在磷脂酶 C 的参与下水解生成的第二信使。它与内质网受体结合后，可激活钙通道，提高细胞内钙浓度。D-myo-Inositol-2,4,5-triphosphate (sodium salt) 还是大鼠肝脏IP3受体的部分激动剂，适用于研究钙信号传导路径。

D-myo-Inositol-1,3,4-triphosphate (sodium) 是一种与信号传导相关的肌醇多磷酸异构体。通过抑制 Ins(3,4,5,6)-P4 激酶活性，该化合物可以提高细胞内部的 Ins(3,4,5,6)-P4 浓度，从而阻碍钙激活氯离子通道的功能。此外，D-myo-Inositol-1,3,4-triphosphate (sodium) 的活性受胞浆中游离钙水平的调控。