p 3

Ebopiprant, also known as OBE-022, is an Oral and Selective Prostaglandin F 2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor. OBE022 exhibits potent tocolytic effects on human tissues ex vivo and animal models in vivo without causing the adverse fetal side effects seen with indomethacin.

JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导，也可阻碍内皮单层细胞迁移和血管生成，影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is a second messenger that promotes the release of calcium ions from the endoplasmic reticulum.

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references and .

N-Demethylansamitocin P-3, a derivative of Ansamitocin, an antitumor ansamycin antibiotic, can be synthesized through the action of Streptomyces minutiscleroticus IFO 13361.

Anti-CEACAM7 Antibody (P3-7B) 为小鼠IgG1, κ 类型嵌合抗体，专门针对CEACAM7(人源)。该抗体的同型对照是 MouseIgG1kappa, Isotype Control。

18:0-20:4 PI(3,4,5)P3 (1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium)) 一种在生化反应中使用的试剂。

18:1 PI(3,4,5)P3 一种在生化反应中使用的试剂。

Ganglioside GM1-bindingpeptidesp3 为一种人工合成多肽，具备与GM1神经节苷脂的五糖部分进行特异性结合的能力。该多肽的动态转变对于理解GM1在多种受体功能中的作用至关重要，特别是在霍乱毒素感染的常见途径上。此外，Ganglioside GM1-bindingpeptidesp3 还常被应用于研究GM1与其配体之间的相互作用。

Ansamitocin P 3' (Maytansinol butyrate) 是一种具有抗肿瘤活性的抗体-药物偶联细胞毒素。

CBP p300-IN-3 (P300 CBP-IN-3) 是一种组蛋白乙酰转移酶抑制剂。

p-3-Methylamino propyl phenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125046。

Ansamitocin p-3 (Maytansinol isobutyrate) 是一种微管抑制剂，对微管蛋白聚合的 IC50 为 3.4 μM。

Ansamitocin P-3 (GMP)是 Ansamitocin P-3 的 GMP 级别试剂。Ansamitocin P-3 是一种微管抑制剂，对微管蛋白聚合的 IC50 为 3.4 μM。

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.

Zosuquidar trihydrochloride (LY-335979 trihydrochloride) 是一种P-糖蛋白抑制剂，Ki 值为 59 nM。

Substance P (3-11)，作为P 物质 (SP) 的片段肽，具备穿透血脑屏障的能力，且对豚鼠回肠显示出收缩活性。

D-myo-Inositol-1,4,5-triphosphate tripotassium (Ins(1,4,5)-P3 tripotassium) 是一种可引发 Ca2+ 动员的细胞内信号转导系统中的第二信使。

D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) 是由磷脂酶 C 介导的磷脂酰肌醇-4,5-二磷酸酯水解在细胞中产生的第二信使。D-myo-Inositol-1,4,5-triphosphate (sodium salt)与 Ins(1,4,5)P3受体结合，会导致钙通道的打开和细胞内钙的增加。

p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1].

p38α inhibitor 3是一种丝裂原活化蛋白激酶P38α的抑制剂，可以有效阻断成肌细胞分化。

p3Ysh-3 是 STEP Phosphatase-GluA2 AMPA 受体相互作用的肽抑制剂，Ki 为 1.09 μM。p3Ysh-3 在东莨菪碱处理的大鼠模型中恢复记忆缺陷并表现出抗焦虑和抗抑郁作用。p3Ysh-3 是一种很有前途的先导化合物，可用于新型认知增强剂和 或行为调节剂。

P3FI-63 是一种选择性 KDM3B 抑制剂（IC50：7 μM），具有抗肿瘤活性，可用于研究融合阳性横纹肌肉瘤和其他转录成瘾癌症。