Name: Notch 1
Brand: TargetMol
SKU: TP3967
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

待询

50 mg

待询

生物活性

产品描述	Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.
体外活性	Notch 1可以通过激活促存活的NF-κB通路来增强小鼠腔内前列腺细胞的存活与增殖。在人前列腺癌细胞系中，下调Notch 1和Jagged1可以抑制细胞体外侵袭及生长。

化学信息

分子量	1500.72
分子式	C₆₂H₉₇N₁₅O₂₂S₃
CAS No.	2408730-51-6
Smiles	[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CS)=O)[C@H](CC)C)=O)CS)=O)CCC(N)=O)=O)NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CS)N)=O)CC(C)C)=O)CC(O)=O)=O)CCC(N)=O)=O)[C@H](CC)C)=O)=O)CCC(O)=O)=O