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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Tropomodulin 3 Polyclonal Antibody

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货号 TMAB-13834

Anti-Tropomodulin 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Tropomodulin 3。Anti-Tropomodulin 3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Tropomodulin 3 Polyclonal Antibody

Anti-Tropomodulin 3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13834

Anti-Tropomodulin 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Tropomodulin 3。Anti-Tropomodulin 3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Tropomodulin 3 Polyclonal Antibody is a Rabbit antibody targeting Tropomodulin 3. Anti-Tropomodulin 3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm > cytoskeleton.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Originally isolated from human erythrocytes, the tropomodulin (TMOD) family of proteins cap the pointed end of Actin filaments. A component of the membrane skeleton, tropomodulin binds to the amino-terminus of Tropomyosin, which coats the surface of Actin, and thus blocks the elongation and depolymerization of Actin filaments. Four tropomodulin isoforms, tropomodulin 1-4, have been characterized in humans. Tropomodulin expression is isoform-specific; tropomodulin 3 is expressed ubiquitously, whereas tropomodulin 2 and tropomodulin 4 are expressed in neuronal tissue and muscle, respectively. Ubiquitous expression of seven tropomodulin 3 transcripts, ranging in size between 1 and 9.5 kb, have been identified by Northern Blot analysis on human tissues. The human TMOD3 gene maps to chromosome 15q21.2, within the same region as the gene for amyotrophic lateral sclerosis 5 (ALS5), and encodes a 352 amino acid protein. Tmod3, the mouse homolog to human TMOD3, is present as early as day 7 in embryonic development and is expressed throughout development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Tropomodulin 3
抗原种属
Human
基因名称
TMOD3
基因ID
29766
蛋白名称
Tropomodulin-3
Uniprot ID
Q9NYL9
功能
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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