D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) is a second messenger produced by the hydrolysis of phosphatidylinositol-4,5-bisphosphate mediated by phospholipase C. Upon binding to receptors on the endoplasmic reticulum, it can open calcium channels and raise intracellular calcium ion concentrations. It also acts as a partial agonist of rat hepatic IP3 receptors. This compound is utilized in the study of calcium signaling pathways.