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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CRMP3 Polyclonal Antibody

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货号 TMAB-04688

Anti-CRMP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CRMP3。Anti-CRMP3 Polyclonal Antibody 可用于 WB。

Anti-CRMP3 Polyclonal Antibody

Anti-CRMP3 Polyclonal Antibody

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货号 TMAB-04688

Anti-CRMP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CRMP3。Anti-CRMP3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CRMP3 Polyclonal Antibody is a Rabbit antibody targeting CRMP3. Anti-CRMP3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum. It is cleaved by Calpain to produce a p54 N-terminal fragment. This cleavage product translocates to the nucleus and induces neuronal death in response to excitotoxicity and cerebral ischemia.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CRMP3
抗原种属
Human
基因名称
DPYSL4
基因ID
10570
蛋白名称
Dihydropyrimidinase-related protein 4
Uniprot ID
O14531
功能
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
化学信息
分子量Theoretical: 62 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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