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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-WISP3 Polyclonal Antibody

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货号 TMAB-14177

Anti-WISP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 WISP3。Anti-WISP3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-WISP3 Polyclonal Antibody

Anti-WISP3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14177

Anti-WISP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 WISP3。Anti-WISP3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-WISP3 Polyclonal Antibody is a Rabbit antibody targeting WISP3. Anti-WISP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Horse,Rabbit,Sheep,Monkey)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine. Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Wnt-induced secreted protein (WISP)-1, WISP-2 and WISP-3 are members of the CCN family of growth factors, which include connective tissue growth factor (CTGF) and Cyr61. WISP-1, WISP-2 and WISP-3 share significant sequence similarity, including four conserved cysteine-rich domains, and they are believed to function as dimers in their active forms. WISP-1 expression is observed in various tissues including adult heart, kidney and spleen, while WISP-2 expression predominates in skeletal muscle, colon and ovary. Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, and they are also more highly expressed in human colon tumors, suggesting that these proteins may participate in tumor development. WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization.
抗原信息
免疫原
KLH conjugated synthetic peptide: human WISP3
抗原种属
Human
基因名称
CCN6
基因ID
8838
蛋白名称
Cellular communication network factor 6
Uniprot ID
O95389
功能
Appears to be required for normal postnatal skeletal growth and cartilage homeostasis.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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