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Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

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Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody
产品编号 TMAC-01731
别名 Serine/threonine protein kinase GSK3A, Phospho-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Tyr216, 279), GSK3alpha, GSK3A/GSK3B (p-Y216, 279), GSK3A/GSK3B (p-Tyr216, 279), Gsk3a, GSK-3 alpha, GSK 3A, GSK 3 alpha, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase 3 alpha, DKFZp686D0638

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-GSK3B (Tyr279, 216)。Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody 可用于 IF,WB,IHC,ELISA。

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody
产品编号 TMAC-01731 别名 Serine/threonine protein kinase GSK3A, Phospho-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Tyr216, 279), GSK3alpha, GSK3A/GSK3B (p-Y216, 279), GSK3A/GSK3B (p-Tyr216, 279), Gsk3a, GSK-3 alpha, GSK 3A, GSK 3 alpha, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase 3 alpha, DKFZp686D0638

Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-GSK3B (Tyr279, 216)。Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody 可用于 IF,WB,IHC,ELISA。

规格价格库存数量
50 μL
¥ 1,495
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100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr279, 216). Anti-Phospho-GSK3B (Tyr279, 216) Polyclonal Antibody can be used in IF,WB,IHC,ELISA.
别名Serine/threonine protein kinase GSK3A, Phospho-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Y216, 279), p-GSK3A/GSK3B (Tyr216, 279), GSK3alpha, GSK3A/GSK3B (p-Y216, 279), GSK3A/GSK3B (p-Tyr216, 279), Gsk3a, GSK-3 alpha, GSK 3A, GSK 3 alpha, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase 3 alpha, DKFZp686D0638
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GSK3α/β (Phospho-Tyr279/216) Antibody TMAC-01731 (left) or the same antibody preincubated with blocking peptide (right).
2. Immunofluorescence staining of methanol-fixed Hela cells using GSK3α/β (Phospho-Tyr279/216) Antibody TMAC-01731.
3. Western blot analysis of extracts from 293 cells untreated or treated with PMA using GSK3α/β (Phospho-Tyr279/216) Antibody TMAC-01731.
4. Immunofluorescence staining of methanol-fixed MEF cells using GSK3α/β (Phospho-Tyr279/216) Antibody TMAC-01731.
应用
IF
WB
IHC
ELISA
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 279/216 (V-S-Y(p)-I-C) derived from Human GSK3α/β
抗原种属
human
Uniprot ID
P49840
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pGSK3A/GSK3B (Y216, 279)pGSK3A/GSK3B (Tyr216, 279)GSK3A/GSK3B (pY216, 279)GSK3A/GSK3B (pTyr216, 279)GSK3A/GSK3B (phospho-Y216, 279)GSK3A/GSK3B (phospho-Tyr216, 279)

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