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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DUSP3 Polyclonal Antibody

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货号 TMAB-05345

Anti-DUSP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUSP3。Anti-DUSP3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DUSP3 Polyclonal Antibody

Anti-DUSP3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05345

Anti-DUSP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DUSP3。Anti-DUSP3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-DUSP3 Polyclonal Antibody is a Rabbit antibody targeting DUSP3. Anti-DUSP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human VHR/DUSP3
抗原种属
Human
基因名称
DUSP3
基因ID
1845
蛋白名称
Dual specificity protein phosphatase 3
Uniprot ID
P51452
功能
Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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