购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

一键复制产品信息
Rating icon 还可以
产品编号 T37028Cas号 1628353-02-5
别名 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

一键复制产品信息
Rating icon 还可以
产品编号 T37028 别名 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)Cas号 1628353-02-5

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.

规格价格库存数量
100 μg
¥ 1,190
35日内发货
500 μg
¥ 5,220
35日内发货
1 mg
¥ 9,130
35日内发货
5 mg
¥ 39,700
35日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates.
别名PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
化学信息
分子量1138.9
分子式C41H78Na4O22P4
CAS No.1628353-02-5
密度no data available
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
CHCl3:CH3OH:H2O (2.5:3:1): 3.8 mg/mL (3.34 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (8.78 mM), Sonication is recommended.
溶液配制表
PBS (pH 7.2)
1mg5mg10mg50mg
5 mM0.1756 mL0.8780 mL1.7561 mL8.7804 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments 一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300/ PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

PtdIns (3,4,5) P3 (1,2 dipalmitoyl) (sodium salt)PtdIns(3,4,5)P3 (1,2dipalmitoyl) (sodium salt)PtdIns-(3,4,5)-P-3 (1,2-dipalmitoyl) (sodium salt)PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | purchase PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) cost | order PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) chemical structure | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) formula | PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt) molecular weight