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Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody

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货号 TMAB-13623

Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNFAIP3 interacting protein 3。Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody

Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13623

Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TNFAIP3 interacting protein 3。Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody is a Rabbit antibody targeting TNFAIP3 interacting protein 3. Anti-TNFAIP3 interacting protein 3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TNFAIP3 interacting protein 3/ABIN3
抗原种属
Human
基因名称
TNIP3
基因ID
79931
蛋白名称
TNFAIP3-interacting protein 3
Uniprot ID
Q96KP6
功能
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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