A3-APO is an antimicrobial peptide that exhibits significant antibacterial activity through a dual mechanism of action (membrane lysis and inhibition of intracellular targets). It can neutralize bacterial toxins and enhance the expression of anti-inflammatory cytokines (such as IL-4 and IL-10) without leading to resistance. A3-APO also accelerates wound healing in burn-infected mouse models of Acinetobacter baumannii and Staphylococcus aureus.