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Anti-GM2A Antibody (4Z337)
还可以产品编号 TMAY-02554
别名 SAP-3, GM2-AP, GM2 ganglioside activator
Anti-GM2A Antibody (4Z337) 是一种 Mouse 抗体，靶向 GM2A。Anti-GM2A Antibody (4Z337) 可用于 ELISA。
Anti-GM2A Antibody (4Z337)
Anti-GM2A Antibody (4Z337)
还可以产品编号 TMAY-02554 别名 SAP-3, GM2-AP, GM2 ganglioside activator
Anti-GM2A Antibody (4Z337) 是一种 Mouse 抗体，靶向 GM2A。Anti-GM2A Antibody (4Z337) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GM2A Antibody (4Z337) is a Mouse antibody targeting GM2A. Anti-GM2A Antibody (4Z337) can be used in ELISA. |
| 别名 | SAP-3, GM2-AP, GM2 ganglioside activator |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4Z337 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GM2A (rh GM2A; TMPY-02765; AAA35907.1; Met1-Ile193). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phospholipase activity. GM2A binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. GM2A acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB), also known as Tay-Sachs disease AB variant. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human GM2A protein (TMPY-02765) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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