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顶部生物活性储存和溶解信息计算器

Anti-GM2A Antibody (4Z337)

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产品编号 TMAY-02554

别名 SAP-3, GM2-AP, GM2 ganglioside activator

Anti-GM2A Antibody (4Z337) 是一种 Mouse 抗体，靶向 GM2A。Anti-GM2A Antibody (4Z337) 可用于 ELISA。

Anti-GM2A Antibody (4Z337)

Anti-GM2A Antibody (4Z337)

一键复制产品信息
Rating icon 还可以
产品编号 TMAY-02554 别名 SAP-3, GM2-AP, GM2 ganglioside activator

Anti-GM2A Antibody (4Z337) 是一种 Mouse 抗体，靶向 GM2A。Anti-GM2A Antibody (4Z337) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,684
5日内发货
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产品介绍

生物活性
产品描述
Anti-GM2A Antibody (4Z337) is a Mouse antibody targeting GM2A. Anti-GM2A Antibody (4Z337) can be used in ELISA.
别名SAP-3, GM2-AP, GM2 ganglioside activator
Ig Type
Mouse IgG1
克隆号
4Z337
交叉反应
Human
特异性
Human GM2A
No cross-reactivity in ELISA with
Insect cell lysate
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GM2A (rh GM2A; TMPY-02765; AAA35907.1; Met1-Ile193).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phospholipase activity. GM2A binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. GM2A acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB), also known as Tay-Sachs disease AB variant.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human GM2A protein (TMPY-02765)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

SAP3SAP 3

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