|
TMPY-00857
|
IL-2RG Protein, Mouse, Recombinant (His & hFc)
gamma(c),interleukin 2 receptor, gamma,[g]c,gc,γ(c)...
|
Mouse
|
HEK293 Cells
|
|
IL-2RG Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.3 kDa and the accession number is P34902. |
|
TMPJ-00759
|
VDB Protein, Human, Recombinant (His)
Group-Specific Component,DBP,VDB,GC,Gc-Glo...
|
Human
|
HEK293 Cells
|
|
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on... |
|
TMPY-06507
|
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc)
gc,[g]c,interleukin 2 receptor, γ,γ(c),CD132,interl...
|
Mouse
|
HEK293 Cells
|
|
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is NP_038591.1. |
|
TMPY-01837
|
IL-2RG Protein, Mouse, Recombinant (His)
gamma(c),interleukin 2 receptor, γ,interleukin 2 receptor, g...
|
Mouse
|
HEK293 Cells
|
|
IL-2RG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P34902. |
|
TMPJ-00911
|
GUCY2C Protein, Human, Recombinant (hFc)
GUC2C,STAR,hSTAR,GC-C,STA receptor,GUCY2C,Guanylyl ...
|
Human
|
HEK293 Cells
|
|
GUCY2C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P25092. |
|
TMPY-06886
|
HSV 2 (strain 333) Glycoprotein C/gC Protein (His)
|
HSV2
|
HEK293 Cells
|
|
HSV 2 (strain 333) Glycoprotein C/gC Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.69 kDa and the accession number is P06475. |
|
TMPK-00990
|
GUCY2C Protein, Mouse, Recombinant (His & Avi)
GC-C,STAR,DIAR6,GCC,GUC2CEC 4.6.1.2,STA re...
|
Mouse
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. |
|
TMPK-00991
|
GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated
EC 4.6.1,Guanylyl cyclase C,MUCIL,GUC2CEC 4.6.1.2,GUC2C,STA ...
|
Mouse
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.01 kDa and the accession number is Q3UWA6-1. |
|
TMPK-01388
|
GUCY2C Protein, Canine, Recombinant (aa 21-430, His)
GC-C,GUCY2C,STAR,EC 4.6.1,STA receptor,GCC...
|
Canine
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Canine, Recombinant (aa 21-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.6 kDa and the accession number is F1PAG3. |
|
TMPK-00856
|
GUCY2C Protein, Human, Recombinant (His & Avi)
GCC,STAR,STA receptor,Guanylyl cyclase C,EC 4.6.1,G...
|
Human
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 48.8 kDa and the accession number is P25092-1. |
|
TMPK-01279
|
GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His)
GUC2CEC 4.6.1.2,GCC,Guanylyl cyclase C,STA receptor...
|
Cynomolgus
|
HEK293 Cells
|
|
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. GUCY2C Protein, Cynomolgus, Recombinant (aa 24-430, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.2 kDa and the accession number is XP_005570270.1. |
|
TMPJ-00910
|
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated
Intestinal guanylate cyclase,STAR,STA receptor,hSTAR,Heat-st...
|
Human
|
HEK293 Cells
|
|
GUCY2C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 65-110 KDa and the accession number is P25092. |
|
TMPJ-01288
|
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of...
|
Human
|
E. coli
|
|
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... |
|
TMPY-01416
|
OLFM4 Protein, Human, Recombinant (His)
hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomed...
|
Human
|
HEK293 Cells
|
|
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed... |
|
TMPY-03443
|
NDRG1 Protein, Human, Recombinant (His)
TARG1,PROXY1,RIT42,NDR1,DRG1,RTP,TDD5,CMT4D,CAP43,NMSL,N-myc...
|
Human
|
E. coli
|
|
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro... |
|
TMPY-05357
|
GCDH Protein, Human, Recombinant (His)
ACAD5,glutaryl-CoA dehydrogenase,GCD
|
Human
|
Baculovirus Insect Cells
|
|
GCDH Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is Q92947-1. |
|
TMPH-00007
|
HMGCR Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs. |
|
TMPH-01382
|
GCGR Protein, Human, Recombinant (E. coli, His & Myc)
|
Human
|
E. coli
|
|
GCGR Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P47871. |
|
TMPH-01077
|
UGCG Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
UGCG Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 47.7 kDa and the accession number is Q16739. |
|
TMPY-03412
|
GGCT Protein, Human, Recombinant (His)
gamma-glutamylcyclotransferase,C7orf24,GGC,γ-glutam...
|
Human
|
E. coli
|
|
GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria with resultant induction of apoptosis. Pseudogenes of GGCT gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 2. Alternatively spliced transcript variants... |
|
TMPH-02476
|
HMGCR Protein, Mouse, Recombinant (His)
|
Mouse
|
E. coli
|
|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.4 kDa and the accession number is Q01237. |
|
TMPJ-00742
|
GCG Protein, Human, Recombinant (His)
Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1,OXM,Glucagon,GL...
|
Human
|
HEK293 Cells
|
|
Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin.... |
|
TMPH-02675
|
GCGR Protein, Mouse, Recombinant (GST)
|
Mouse
|
E. coli
|
|
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. ... |
|
TMPJ-01393
|
PGCP Protein, Mouse, Recombinant (His)
Plasma glutamate carboxypeptidase,Hls2,Hematopoietic lineage...
|
Mouse
|
HEK293 Cells
|
|
Carboxypeptidase Q (Cpq) is a member of the peptidase M28 family. PGCP is involved in a number of fundamental biological processes such as the hydrolysis of circulating peptides, catalyzing the hydrolysis of dipeptides with unsubstituted terminals into amino acids. Carboxypeptidase may play an important role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor. The monomeric form is inactive while the homodimer is active. |
|
TMPH-03194
|
GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc)
|
Pyrococcus horikoshii
|
E. coli
|
|
Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also utilize GTP, CTP, UTP, ADP or pyrophosphate as phosphate donor. GCK Protein, Pyrococcus horikoshii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is O58231. |
|
TMPY-02513
|
Pepsinogen C/PGC Protein, Rat, Recombinant (His)
progastricsin (pepsinogen C)
|
Rat
|
HEK293 Cells
|
|
Pepsinogen C/PGC Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A6JII4. |
|
TMPJ-00926
|
GCA Protein, Human, Recombinant (GST)
GCA,Grancalcin,GCL
|
Human
|
E. coli
|
|
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and ... |
|
TMPH-03557
|
HlgC Protein, S. aureus, Recombinant (His)
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.6 kDa and the accession number is Q7A3S2. |
|
TMPH-02717
|
HMGCS1 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse
|
E. coli
|
|
Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. HMGCS1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.6 kDa and the accession number is Q8JZK9. |
|
TMPH-01387
|
GCKR Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, R... |
|
TMPH-01388
|
GCKR Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, R... |
|
TMPY-01731
|
Pepsinogen C/PGC Protein, Human, Recombinant (His)
progastricsin (pepsinogen C),PGII,PEPC
|
Human
|
HEK293 Cells
|
|
Pepsinogen C/PGC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P20142-1. |
|
TMPH-03444
|
GCY1 Protein, S. cerevisiae, Recombinant (His)
|
Saccharomyces cerevisiae
|
P. pastoris (Yeast)
|
|
Glycerol dehydrogenase involved in glycerol catabolism under microaerobic conditions. Has mRNA binding activity. GCY1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is P14065. |
|
TMPY-03503
|
GCSH Protein, Human, Recombinant (His)
glycine cleavage system protein H (aminomethyl carrier),NKH,...
|
Human
|
E. coli
|
|
Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic h... |
|
TMPH-03556
|
HlgC Protein, S. aureus, Recombinant (E. coli, His)
|
Staphylococcus aureus
|
E. coli
|
|
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.6 kDa and the accession number is Q7A3S2. |
|
TMPY-03463
|
GCAP1 Protein, Human, Recombinant (His & GST)
guanylate cyclase activator 1A (retina),CORD14,GCAP...
|
Human
|
Baculovirus Insect Cells
|
|
GCAP1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.7 kDa and the accession number is P43080. |
|
TMPH-00629
|
Gamma-GCS Protein, E. coli, Recombinant (His & SUMO)
|
E. coli
|
E. coli
|
|
N/A. Gamma-GCS Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.3 kDa and the accession number is P0A6W9. |
|
TMPH-01383
|
GCGR Protein, Human, Recombinant (His & Myc)
|
Human
|
HEK293 Cells
|
|
GCGR Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.1 kDa and the accession number is P47871. |
|
TMPY-03554
|
GCAP1 Protein, Human, Recombinant
GCAP,dJ139D8.6,GUCA,GCAP1,COD3,C6orf131,GU...
|
Human
|
Baculovirus Insect Cells
|
|
GCAP1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 23.1 kDa and the accession number is P43080. |
|
TMPK-00925
|
Noggin/NOG Protein, Mouse, Recombinant
NOG,SYM1,SYNS1,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG... |
|
TMPJ-01456
|
Mucin-17/MUC17 Protein, Human, Recombinant (His)
Mucin-17, MUC-17, MUC17, MUC3, MUC-3
|
Human
|
HEK293 Cells
|
|
Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ... |
|
TMPK-00926
|
Noggin/NOG Protein, Mouse, Recombinant (His & Flag)
SYNS1,NOG,SYM1,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β‑catenin, EGFR, ERK and Akt. Noggin/NOG... |
|
TMPH-03310
|
GUCY2C Protein, Rat, Recombinant (His & Myc)
|
Rat
|
HEK293 Cells
|
|
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin. GUCY2C Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 51.4 kDa and the accession number is P23897. |
|
TMPH-02303
|
Vasculin Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Functions as a GC-rich promoter-specific transactivating transcription factor. Vasculin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.8 kDa and the accession number is Q86WP2. |
|
TMPH-01013
|
BMP-15 Protein, Human, Recombinant (His & Myc)
BMP15,GDF-9B,BMP-15,Bone morphogenetic protein 15,GDF9B,Grow...
|
Human
|
E. coli
|
|
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. BMP-15 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is O95972. |
|
TMPY-03047
|
Stathmin 1 Protein, Human, Recombinant (His)
SMN,OP18,stathmin 1,LAP18,C1orf215,PP17,Lag,PP19,PR22
|
Human
|
E. coli
|
|
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and prom... |
|
TMPY-00116
|
MTH1 Protein, Human, Recombinant (His)
MTH1,nudix (nucleoside diphosphate linked moiety X)-type mot...
|
Human
|
E. coli
|
|
NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1 protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Cancers can survive the oxidative conditions by upregulating nucleoside diphosphate lin... |
|
TMPY-04934
|
Serpin A3n Protein, Rat, Recombinant (His)
serine (or cysteine) peptidase inhibitor, clade A, member 3N
|
Rat
|
HEK293 Cells
|
|
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal muscle resident proteases during injury or dystrophic disease, which stabilizes the sarcolemma leading to less myofiber degeneration and increased regeneration. |
|
TMPY-04768
|
PRPS2 Protein, Human, Recombinant (His)
PRPS2,PRSII,phosphoribosyl pyrophosphate synthetase 2
|
Human
|
E. coli
|
|
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via the p53/Bcl-2/caspases signaling pathway. The gene for PRS II (PRPS2) is located at a different region of the X chromosome, namely Xpter-a21. The promoter region of the human PRPS2 gene was also GC-rich and contained a TATA-like sequence, four Sp1 binding sites and a homopyrimidine... |
|
TMPY-05800
|
IKB beta/NFKBIB Protein, Human, Recombinant (GST)
NFKB inhibitor β,NFKB inhibitor beta,TRIP9,IKBB,IKB β/NFKBIB
|
Human
|
E. coli
|
|
NFKBIB (NFKB Inhibitor Beta) is a Protein Coding gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. NF-kappaB regulation involves the inhibitor pr... |
沪公网安备 31010602006700号