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Anti-CEACAM3 Antibody (7Z451)
还可以产品编号 TMAY-02152
别名 W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3
Anti-CEACAM3 Antibody (7Z451) 是一种 Mouse 抗体，靶向 CEACAM3。Anti-CEACAM3 Antibody (7Z451) 可用于 FCM。
Anti-CEACAM3 Antibody (7Z451)
Anti-CEACAM3 Antibody (7Z451)
还可以产品编号 TMAY-02152 别名 W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3
Anti-CEACAM3 Antibody (7Z451) 是一种 Mouse 抗体，靶向 CEACAM3。Anti-CEACAM3 Antibody (7Z451) 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CEACAM3 Antibody (7Z451) is a Mouse antibody targeting CEACAM3. Anti-CEACAM3 Antibody (7Z451) can be used in FCM. |
| 别名 | W282, W264, MGC119875, CGM1, CEA, CD66D, carcinoembryonic antigen related cell adhesion molecule 3 |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7Z451 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of anti-human CEACAM3 (CD66d) on human whole blood granulocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable granulocytes. Flow cytometry was performed using a BD FACS Calibur Flow Cytometer System. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM3 / CD66d (rh CEACAM3 / CD66d; TMPY-01850; NP_001806.2; Met1-Gly155). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). CEACAM3 mediates phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3. CEACAM3 is characterized by rapid stimulation of the GTPase Rac. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human CEACAM3 / CD66d protein (TMPY-01850) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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