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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PPARGC1A Polyclonal Antibody 2

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货号 TMAB-11654

Anti-PPARGC1A Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PPARGC1A。Anti-PPARGC1A Polyclonal Antibody 2 可用于 IHC-P,WB,ICC/IF,IHC-Fr,IF。

Anti-PPARGC1A Polyclonal Antibody 2

Anti-PPARGC1A Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-11654

Anti-PPARGC1A Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PPARGC1A。Anti-PPARGC1A Polyclonal Antibody 2 可用于 IHC-P,WB,ICC/IF,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-PPARGC1A Polyclonal Antibody 2 is a Rabbit antibody targeting PPARGC1A. Anti-PPARGC1A Polyclonal Antibody 2 can be used in IHC-P,WB,ICC/IF,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Goat)
应用IHC-PWBICC/IFIHC-FrIF
推荐剂量
IHC-P: 1:100-500; WB: 1:500-2000; ICC/IF: 1:50-100; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Heart, skeletal muscle, liver and kidney. Expressed at lower levels in brain and pancreas and at very low levels in the intestine and white adipose tissue. In skeletal muscle, levels were lower in obese than in lean subjects and fasting induced a 2-fold increase in levels in the skeletal muscle in obese subjects.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.
抗原信息
免疫原
Recombinant Protein: human PPARGC1A
抗原种属
Human
基因名称
PPARGC1A
基因ID
10891
蛋白名称
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Uniprot ID
Q9UBK2
功能
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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