d 3

D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.

5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol）是维生素 D3 的异构体，经光照后在皮肤表面由 Vitamin D3 转化而来。

HTT-D3 是一种具有口服活性且高效的亨廷顿剪接调节剂，能够促使 HTT mRNA 降解，诱导 HTT 蛋白水平降低 ，并抑制 p-糖蛋白 (P-gp) 的外排作用，因而可应用于亨廷顿病的研究。

Vitamin D3 (cholecalciferol) 是维生素 D 的一种天然存在形式，代谢激活后可诱导细胞分化和癌细胞增殖。Vitamin D3 可用于构建肾结石模型，也是免疫、肿瘤领域的重要研究靶点。

Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM；对Slingshot 2 的Ki 为 3.9 μM。

3-Hydroxy agomelatine-D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine (T10114) is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

4-Hydroxyatomoxetine-D3 is a deuterium labeled 4-Hydroxyatomoxetine. 4-Hydroxyatomoxetine (T10145) is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine (T10145) is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.

Acetazolamide-D3 is a deuterium-labeled Acetazolamide. Acetazolamide (T0813) is a potent carbonic anhydrase inhibitor.

Apixaban 13C,D3是Apixaban (T1736)的氘代标记物，可用于同位素示踪。是一种选择性的凝血因子 Xa (Factor Xa)抑制剂，用于研究血栓栓塞。

Clomipramine-D3 is the deuterium-labeled Clomipramine. Clomipramine (T21013) is a serotonin transporter,norepinephrine transporter dopamine transporter blocker (Ki: 0.14,54 and 3 nM).

Clomipramine-D3 hydrochloride is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter,norepinephrine transporter dopamine transporter blocker (Ki: 0.14,54 and 3 nM).

Doxepin-D3 hydrochloride 是一种氘标记、稳定同位素标记的盐酸多塞平类似物，主要用作定量分析的内标。Doxepin hydrochloride（T1540）是一种三环类抗抑郁药(TCA)和镇静剂，用于治疗抑郁、焦虑和失眠。

Doxercalciferol-D3 is the deuterated form of Doxercalciferol (T6112)and ACTS as vitamin D receptor activator (VDRA),which is a vitamin D2 analogue.

Duloxetine-D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI)with a Ki of 4.6 nM,used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ( (S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride (T1471).

Enzalutamide-D3是雄激素受体拮抗剂Enzalutamide (T6002)的氘代标记形式，在 LNCaP 前列腺癌细胞中保持显著的抗雄激素及抗肿瘤活性，IC50 为 36 nM，主要用于药代动力学、代谢示踪及药物相互作用研究。

Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium-D3 bromide is a deuterium labeled Fenpiverinium bromide.

Ibuprofen-D3 is a deuterium labeled Ibuprofen. Ibuprofen (T1394) is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

Ivabradine-D3 hydrochloride is a new If inhibitor with IC50 of 2.9 μM,and used as a pure heart rate lowering agent. Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride (T2535).

Linezolid-D3是Linezolid（T0391）的氘代标记物，可用于同位素示踪。Linezolid是一种用于阻断细菌蛋白质合成起始过程的合成抗生素。Linezolid-D3可用于抗菌药代动力学及基于示踪的生化研究体系，以研究蛋白质合成抑制机制及细菌翻译模型中的抗生素分布同位素追踪。

Meloxicam-D3 is deuterium labeled Meloxicam. Meloxicam (T0826) is a non-steroidal antiinflammatory agent,inhibits COX activity, (Target:COX-1; IC50: 36.6 μM ; (Target:COX-2; IC50: 0.49 μM).

Methimazole-D3, a deuterium-labeled version of Methimazole, serves as an antithyroid medication for treating hyperthyroidism in both humans and animals.

Methylnaltrexone-D3 bromide is the deuterium-labeled Methylnaltrexone Bromide.

Mirtazapine-D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .

Naratriptan-D3 hydrochloride,the deuterium-labeled form of Naratriptan Hydrochloride (T6602),is a selective agonist of the 5-HT1 receptor subtype.