d 3

D-3, a phosphorpeptide, is an efficient, simple, and specific iPSC-eliminating agent.

5,6-trans-Vitamin D3（5,6-trans-Cholecalciferol）是维生素 D3 的异构体，经光照后在皮肤表面由 Vitamin D3 转化而来。

HTT-D3 是一种具有口服活性且高效的亨廷顿剪接调节剂，能够促使 HTT mRNA 降解，诱导 HTT 蛋白水平降低 ，并抑制 p-糖蛋白 (P-gp) 的外排作用，因而可应用于亨廷顿病的研究。

Vitamin D3（Cholecalciferol）是维生素 D 的一种天然存在形式，代谢激活后可诱导细胞分化和癌细胞增殖，并可用于构建肾结石模型。

Slingshot inhibitor D3 (JHN76359) 是具有选择性、竞争性、可逆性的Slingshot 抑制剂。它对Slingshot 1和Slingshot 2具有相似的抑制活性。它对Slingshot 1 的IC50为 3 μM；对Slingshot 2 的Ki 为 3.9 μM。

3-Hydroxy agomelatine-D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine (T10114) is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

4-Hydroxyatomoxetine-D3 is a deuterium labeled 4-Hydroxyatomoxetine. 4-Hydroxyatomoxetine (T10145) is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine (T10145) is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.

Acetazolamide-D3 is a deuterium-labeled Acetazolamide. Acetazolamide (T0813) is a potent carbonic anhydrase inhibitor.

Apixaban 13C,D3是Apixaban (T1736)的氘代标记物，可用于同位素示踪。是一种选择性的凝血因子 Xa (Factor Xa)抑制剂，用于研究血栓栓塞。

Clomipramine-D3 is the deuterium-labeled Clomipramine. Clomipramine (T21013) is a serotonin transporter,norepinephrine transporter dopamine transporter blocker (Ki: 0.14,54 and 3 nM).

Clomipramine-D3 hydrochloride is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter,norepinephrine transporter dopamine transporter blocker (Ki: 0.14,54 and 3 nM).

Doxepin-D3 hydrochloride is a deuterium-labeled doxepin hydrochloride.Doxepin hydrochloride is an oral active tricyclic antidepressant used as a sedative.Doxepin hydrochloride is also an effective CYP450 inhibitor,significantly inhibiting CYP450 2C19 and 1A2.Doxepin hydrochloride is an effective selective histamine receptor H1 antagonist.

Doxercalciferol-D3 is the deuterated form of Doxercalciferol (T6112)and ACTS as vitamin D receptor activator (VDRA),which is a vitamin D2 analogue.

Duloxetine-D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI)with a Ki of 4.6 nM,used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ( (S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride (T1471).

Enzalutamide-D3是雄激素受体拮抗剂Enzalutamide (T6002)的氘代标记形式，在 LNCaP 前列腺癌细胞中保持显著的抗雄激素及抗肿瘤活性，IC50 为 36 nM，主要用于药代动力学、代谢示踪及药物相互作用研究。

Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium-D3 bromide is a deuterium labeled Fenpiverinium bromide.

Ibuprofen-D3 is a deuterium labeled Ibuprofen. Ibuprofen (T1394) is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).

Ivabradine-D3 hydrochloride is a new If inhibitor with IC50 of 2.9 μM,and used as a pure heart rate lowering agent. Ivabradine D3 Hydrochloride is the deuterium labeled Ivabradine hydrochloride (T2535).

Linezolid-D3,a deuterium-labeled version of Linezolid,is a synthetic antibiotic designed to halt the initiation of bacterial protein synthesis.

Meloxicam-D3 is deuterium labeled Meloxicam. Meloxicam (T0826) is a non-steroidal antiinflammatory agent,inhibits COX activity, (Target:COX-1; IC50: 36.6 μM ; (Target:COX-2; IC50: 0.49 μM).

Methimazole-D3, a deuterium-labeled version of Methimazole, serves as an antithyroid medication for treating hyperthyroidism in both humans and animals.

Methylnaltrexone-D3 bromide is the deuterium-labeled Methylnaltrexone Bromide.

Mirtazapine-D3 is a deuterium labeled Mirtazapine. Mirtazapine is an inhibitor of 5-HT receptor .

Naratriptan-D3 hydrochloride,the deuterium-labeled form of Naratriptan Hydrochloride (T6602),is a selective agonist of the 5-HT1 receptor subtype.