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Anti-FOXD3 Monoclonal Antibody (2L13) 是一种 Mouse 抗体,靶向 FOXD3。Anti-FOXD3 Monoclonal Antibody (2L13) 可用于 WB,IHC。
别名 HFH2, Genesis, FOXD3, AIS1
Anti-FOXD3 Monoclonal Antibody (2L13) 是一种 Mouse 抗体,靶向 FOXD3。Anti-FOXD3 Monoclonal Antibody (2L13) 可用于 WB,IHC。

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| 产品描述 | Anti-FOXD3 Monoclonal Antibody (2L13) is a Mouse antibody targeting FOXD3. Anti-FOXD3 Monoclonal Antibody (2L13) can be used in WB,IHC. |
| 别名 | HFH2, Genesis, FOXD3, AIS1 |
| Ig Type | IgG1 |
| 克隆号 | 2L13 |
| 反应种属 | Human,Mouse,Monkey |
| 应用 | WBIHC |
| 推荐剂量 | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation. FoxD3 is required for the maintenance of the mammalian neural crest; FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures. FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human FOXD3 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | FOXD3 |
| 基因ID | |
| 蛋白名称 | Forkhead box protein D3 |
| Uniprot ID |
| 分子量 | Theoretical: 50 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |