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Anti-FHOD3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FHOD3。Anti-FHOD3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-FHOD3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FHOD3。Anti-FHOD3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-FHOD3 Polyclonal Antibody is a Rabbit antibody targeting FHOD3. Anti-FHOD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Chicken,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm; cytoskeleton. Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. |
| 组织特异性 | Expressed in the heart, kidney and brain. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | FHOD3 (formin homology 2 domain containing 3), also known as FHOS2 or KIAA1695, is a 1,422 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one DAD domain, one FH1 domain, one FH2 domain and one GBD/FH3 domain. Expressed in brain, heart and kidney, FHOD3 interacts with intermediate filaments and functions as an Actin-organizing protein that is thought to promote the formation of stress fibers in conjunction with cellular elongation. Multiple isoforms of FHOD3 exist due to alternative splicing events. The gene encoding FHOD3 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| 免疫原 | KLH conjugated synthetic peptide: human Supervillin |
| 抗原种属 | Human |
| 基因名称 | FHOD3 |
| 基因ID | |
| 蛋白名称 | FH1/FH2 domain-containing protein 3 |
| Uniprot ID | |
| 功能 | Actin-organizing protein that may cause stress fiber formation together with cell elongation. |
| 分子量 | Theoretical: 159 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |