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Anti-LCK Monoclonal Antibody (3D619) 是一种 Mouse 抗体,靶向 LCK。Anti-LCK Monoclonal Antibody (3D619) 可用于 WB。
别名 YT16, pp58lck, p56lck, LSK, IMD22
Anti-LCK Monoclonal Antibody (3D619) 是一种 Mouse 抗体,靶向 LCK。Anti-LCK Monoclonal Antibody (3D619) 可用于 WB。

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| 产品描述 | Anti-LCK Monoclonal Antibody (3D619) is a Mouse antibody targeting LCK. Anti-LCK Monoclonal Antibody (3D619) can be used in WB. |
| 别名 | YT16, pp58lck, p56lck, LSK, IMD22 |
| Ig Type | IgG2a |
| 克隆号 | 3D619 |
| 反应种属 | Human |
| 应用 | WB |
| 推荐剂量 | WB: 1/500-1/2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide. |
| 浓度 | 1 mg/mL |
| 研究背景 | Lck (lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human Lck expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | LCK |
| 基因ID | |
| 蛋白名称 | Tyrosine-protein kinase Lck |
| Uniprot ID |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |