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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RND3 Polyclonal Antibody

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货号 TMAB-12277

Anti-RND3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RND3。Anti-RND3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RND3 Polyclonal Antibody

Anti-RND3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12277

Anti-RND3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RND3。Anti-RND3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-RND3 Polyclonal Antibody is a Rabbit antibody targeting RND3. Anti-RND3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi Apparatus; Golgi apparatus membrane; peripheral membrane protein.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Rho family of proteins mediates cytoskeleton organization and cell motility responses. This family contains twenty different members divided into five groups, the Rho-like, Rac-like, Cdc42-like, Rnd and RhoBTB subfamilies. Rho proteins have GTPase activity and bind GTP in their active form and GDP in their inactive form. In their active form they interact with downstream proteins. However, the Rnd subfamily of proteins containing the Rnd1, Rnd2 and RhoE(Rnd3), binds GTP but not GDP and has no GTPase activity. While Rho proteins are required for stress fibre formation in cultured fibroblasts, epithelial and endothelial cells, overexpression of Rnd3 or Rnd1 in the same cells may cause an opposite effect (i.e. decrease in stress fibre). Thus, the Rnd3 protein may act as an antagonist for the Rho proteins either by directly binding to Rho or to other downstream proteins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RND3
抗原种属
Human
基因名称
RND3
基因ID
390
蛋白名称
Rho-related GTP-binding protein RhoE
Uniprot ID
P61587
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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